Patrick Sullivan is a Distinguished Professor in the Department of Genetics and Psychiatry at the University of North Carolina at Chapel Hill and also Professor at the Karolinska Institute in Stockholm, Sweden. He is a founder and the lead principal investigator of the Psychiatric Genomics Consortium as well as a Swedish national complex trait consortium and its extension to Denmark and Norway (focusing on psychiatric disorders). His labs investigate the molecular genetics of schizophrenia, major depressive disorder (including post-partum depression), and eating disorders. He has an outstanding track record of training post-docs and in advancing them to faculty positions and independent R01 funding. Dr Sullivan has 433 total publications including 375 papers (peer-reviewed: published, in press, or submitted) and 58 other contributions (reviews, editorials, comments, invited manuscripts, or chapters). Google Scholar h-index 114. In the past 10 years, essentially all of his empirical papers have had trainees as co-authors.
Research Interests
Key words: complex traits in humans, psychiatric genetics, pharmacogenetics, schizophrenia, major depression, eating disorders
The Sullivan lab aims to understand the genetic and epidemiological basis of a number of important public-health problems. These disorders are etiologically heterogeneous and exhibit complex patterns of inheritance. Developing an understanding of these disorders requires the integration of findings from multiple investigative approaches such as epidemiology, linkage analysis, and association studies. The lab applies these methods to several research areas:
Schizophrenia
This is a chronic and debilitating mental disorder that affects approximately 1% of the human population. Although it is clear that genetics plays a role in schizophrenia, specific genes that have a causal role in the disease have yet to be identified. The Sullivan lab is conducting a series of studies to elucidate its etiology. In addition, pharmacogenetic studies are underway to determine the mechanism of action of antipsychotic drugs that are currently used to treat some of the symptoms of schizophrenia.
Mentor Training:
Publications
Patrick Sullivan in UNC Genetics News

March 3, 2025
Department of Genetics Publications for February 2nd – March 1st, 2025
Department of Genetics faculty, postdocs, students and collaborators published 18 papers during February 2nd - March 1st 2025.

February 6, 2025
Department of Genetics Publications for January 19th – February 1st, 2025
Department of Genetics faculty, postdocs, students and collaborators published 17 papers during January 19th - February 1st 2025.

January 23, 2025
Eight Psychiatric Disorders Share the Same Genetic Causes, Study Says
Building off previous groundbreaking research, a new study identifies specific genetic variants that have significant impacts on brain development and are shared across eight different psychiatric disorders. Targeting these variants could pave the way for treatments that address multiple conditions at once.

December 3, 2024
Department of Genetics Publications for November 10th – 23rd, 2024
Department of Genetics faculty, postdocs, students and collaborators published 19 papers during November 10th - 23rd, 2024.

September 14, 2024
Department of Genetics Publications for September 1st-14th, 2024
Department of Genetics faculty, postdocs, students and collaborators published 23 papers during September 1st - 14th, 2024.

August 13, 2024
Researchers Highlight the Genetic Complexity of Schizophrenia
A new review article written by Patrick Sullivan, MD, FRANZCP, the Yeargan Distinguished Professor of Psychiatry and Genetics, outlines the genetic foundations for schizophrenia.

August 5, 2024
Department of Genetics Publications for July 21st – August 3rd, 2024
Department of Genetics faculty, postdocs, students and collaborators published 13 papers during July 21st - August 3rd 2024.

June 24, 2024
Department of Genetics Publications for June 9th – 22nd, 2024
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during June 9th - 22nd 2024.

April 15, 2024
Department of Genetics Publications for March 31st – April 13th, 2024
Department of Genetics faculty, postdocs, students and collaborators published 9 papers during March 31st - April 13th 2024.

February 19, 2024
Department of Genetics Publications for February 4th – 17th, 2024
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during February 4th - 17th 2024.