Patrick Sullivan is a Distinguished Professor in the Department of Genetics and Psychiatry at the University of North Carolina at Chapel Hill and also Professor at the Karolinska Institute in Stockholm, Sweden. He is a founder and the lead principal investigator of the Psychiatric Genomics Consortium as well as a Swedish national complex trait consortium and its extension to Denmark and Norway (focusing on psychiatric disorders). His labs investigate the molecular genetics of schizophrenia, major depressive disorder (including post-partum depression), and eating disorders. He has an outstanding track record of training post-docs and in advancing them to faculty positions and independent R01 funding. Dr Sullivan has 433 total publications including 375 papers (peer-reviewed: published, in press, or submitted) and 58 other contributions (reviews, editorials, comments, invited manuscripts, or chapters). Google Scholar h-index 114. In the past 10 years, essentially all of his empirical papers have had trainees as co-authors.
Research Interests
Key words: complex traits in humans, psychiatric genetics, pharmacogenetics, schizophrenia, major depression, eating disorders
The Sullivan lab aims to understand the genetic and epidemiological basis of a number of important public-health problems. These disorders are etiologically heterogeneous and exhibit complex patterns of inheritance. Developing an understanding of these disorders requires the integration of findings from multiple investigative approaches such as epidemiology, linkage analysis, and association studies. The lab applies these methods to several research areas:
Schizophrenia
This is a chronic and debilitating mental disorder that affects approximately 1% of the human population. Although it is clear that genetics plays a role in schizophrenia, specific genes that have a causal role in the disease have yet to be identified. The Sullivan lab is conducting a series of studies to elucidate its etiology. In addition, pharmacogenetic studies are underway to determine the mechanism of action of antipsychotic drugs that are currently used to treat some of the symptoms of schizophrenia.
Mentor Training:
Publications
Patrick Sullivan in UNC Genetics News
August 13, 2024
Researchers Highlight the Genetic Complexity of Schizophrenia
A new review article written by Patrick Sullivan, MD, FRANZCP, the Yeargan Distinguished Professor of Psychiatry and Genetics, outlines the genetic foundations for schizophrenia.
August 5, 2024
Department of Genetics Publications for July 21st – August 3rd, 2024
Department of Genetics faculty, postdocs, students and collaborators published 13 papers during July 21st - August 3rd 2024.
June 24, 2024
Department of Genetics Publications for June 9th – 22nd, 2024
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during June 9th - 22nd 2024.
April 15, 2024
Department of Genetics Publications for March 31st – April 13th, 2024
Department of Genetics faculty, postdocs, students and collaborators published 9 papers during March 31st - April 13th 2024.
February 19, 2024
Department of Genetics Publications for February 4th – 17th, 2024
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during February 4th - 17th 2024.
February 15, 2024
First came love, then came science
Cynthia Bulik and Patrick Sullivan have created a life full of adventure and research spanning decades, continents, and disciplines.
December 15, 2023
Institute brings together UNC suicide prevention researchers
Several researchers at the University of North Carolina at Chapel Hill are focusing their efforts on suicide-related intervention research, but linking their work across schools and departments can be daunting.
November 20, 2023
Genetics Faculty Members Hoadley, Perou, Sullivan and Ting Named to Clarivate’s 2023 List of Highly Cited Researchers
Drs. Katie Hoadley, Chuck Perou, Patrick Sullivan, and Jenny Ting have been recognized as 2023 Highly Cited Researchers.
October 23, 2023
Department of Genetics Publications for October 8th – 21st, 2023
Department of Genetics faculty, postdocs, students and collaborators published 9 papers during October 8th - 21st 2023.
October 9, 2023
Department of Genetics Publications for September 24th – October 7th, 2023
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during September 24th - October 7th 2023.