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Marsico Lung Institute faculty, postdoc, student, and collaborator publications for January 2025 included papers appearing in The Lancet: Respiratory Medicine, The American Journal of Respiratory and Critical Care Medicine, and Nucleic Acids Research. Check out the full list below:

  1. Farzal Z, Sullivan KM, Zariwala MA, Thorp BD, Senior BA, Ebert CS Jr, Davis S, Leigh MW, Knowles MR, Kimple AJ. Olfactory Dysfunction in Primary Ciliary Dyskinesia. OTO Open. 2025 Jan 31;9(1):e70084. doi: 10.1002/oto2.70084. PMID: 39896853; PMCID: PMC11783683.
  2. Sims AC, Schäfer A, Okuda K, Leist SR, Kocher JF, Cockrell AS, Hawkins PE, Furusho M, Jensen KL, Kyle JE, Burnum-Johnson KE, Stratton KG, Lamar NC, Niccora CD, Weitz KK, Smith RD, Metz TO, Waters KM, Boucher RC, Montgomery SA, Baric RS, Sheahan TP. Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity. mSphere. 2025 Jan 30:e0095124. doi: 10.1128/msphere.00951-24. Epub ahead of print. PMID: 39882872.
  3. Hickman E, Carberry V, Carberry C, Cooper B, Mordant AL, Mills A, Sokolsky M, Herring LE, Alexis NE, Rebuli ME, Jaspers I, Sheats K, Rager JE. Respiratory extracellular vesicle isolation optimization through proteomic profiling of equine samples and identification of candidates for cell-of-origin studies. PLoS One. 2025 Jan 24;20(1):e0315743. doi: 10.1371/journal.pone.0315743. PMID: 39854355; PMCID: PMC11760557.
  4. Bayless R, Saini Y. Optimizing Neutrophil Recruitment to Tackle Bacterial Infections? Am J Respir Cell Mol Biol. 2025 Jan 21. doi: 10.1165/rcmb.2024-0575ED. Epub ahead of print. PMID: 39836037.
  5. Smyth TR, Brocke S, Kim YH, Christianson C, Kovalcik KD, Pancras JP, Hays MD, Wu W, An Z, Jaspers I. Human Monocyte-Derived Macrophages Demonstrate Distinct Responses to Ambient Particulate Matter in a Polarization State- and Particle Seasonality-Specific Manner. Chem Res Toxicol. 2025 Jan 20;38(1):73-90. doi: 10.1021/acs.chemrestox.4c00291. PMID: 39704336.
  6. Bhatia A, Preiss AJ, Xiao X, Brannock MD, Alexander GC, Chew RF, Davis H, Fitzgerald M, Hill E, Kelly EP, Mehta HB, Madlock-Brown C, Wilkins KJ, Chute CG, Haendel M, Moffitt R, Pfaff ER; N3C Consortium. Effect of nirmatrelvir/ritonavir (Paxlovid) on hospitalization among adults with COVID-19: An electronic health record-based target trial emulation from N3C. PLoS Med. 2025 Jan 17;22(1):e1004493. doi: 10.1371/journal.pmed.1004493. PMID: 39823513. PMCID: PMC11790232
  7. Stevens EL, Chiel LE, Collins MS, Rama JA, Esther CR Jr, Richard K, Nelson BA, Weiss P, Nuncio B, Turner DA, Boyer D. Mapping Pediatric Pulmonary Milestones 2.0 to Entrustable Professional Activities. ATS Sch. 2025 Jan 15. doi: 10.34197/ats-scholar.2024-0105BR. Epub ahead of print. PMID: 39904503.
  8. DeMeis JD, Roberts JT, Delcher HA, Godang NL, Coley AB, Brown CL, Shaw MH, Naaz S, Dahal A, Alqudah SY, Nguyen KN, Nguyen AD, Paudel SS, Shell JE, Patil SS, Dang H, O’Neal WK, Knowles MR, Houserova D, Gillespie MN, Borchert GM. Long G4-rich enhancers target promoters via a G4 DNA-based mechanism. Nucleic Acids Res. 2025 Jan 11;53(2):gkae1180. doi: 10.1093/nar/gkae1180. PMID: 39658038. PMCID: PMC11754661.
  9. Mwase C, Schworer SA, Gilmore RC, Khan F, Dy ABC, Haber AL, Boucher RC Jr, Randell SH, Mackman N, Park JA. TGF-β Receptor-dependent Tissue Factor Release and Proteomic Profiling of Extracellular Vesicles from Mechanically Compressed Human Bronchial Epithelial Cells. Am J Respir Cell Mol Biol. 2025 Jan 7. doi: 10.1165/rcmb.2024-0130OC. Epub ahead of print. PMID: 39773168.
  10. Faino AV, Gordon WW, Buckingham K, Stilp AM, Pace RG, Raraigh KS, Collaco JM, Zhou YH, Dang H, O’Neal W, Knowles MK, Cutting GR, Rosenfeld M, Bamshad MJ, Gibson RL, Blue EE; Cystic Fibrosis Genome Project. CHP2 Modifies Chronic Pseudomonas aeruginosa Airway Infection Risk in Cystic Fibrosis. Ann Am Thorac Soc. 2025 Jan 2. doi: 10.1513/AnnalsATS.202408-868OC. Epub ahead of print. PMID: 39746161.
  11. Goralski JL, Talati AN, Hardisty EE, Vora NL. Pregnancy in People With Cystic Fibrosis Treated With Highly Effective Modulator Therapy. Obstet Gynecol. 2025 Jan 1;145(1):47-54. doi: 10.1097/AOG.0000000000005732. PMID: 39666984; PMCID: PMC11630662.
  12. Jain R, Goralski JL. Learning from the CFTR modulator baby boom. J Cyst Fibros. 2025 Jan;24(1):3-4. doi: 10.1016/j.jcf.2024.12.003. PMID: 39794183.
  13. Singh D, Brightling CE, Rabe KF, Han MK, Christenson SA, Drummond MB, Papi A, Pavord ID, Molfino NA, Almqvist G, Kotalik A, Hellqvist Å, Gołąbek M, Sindhwani NS, Ponnarambil SS; COURSE study investigators. Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial. Lancet Respir Med. 2025 Jan;13(1):47-58. doi: 10.1016/S2213-2600(24)00324-2. PMID: 39653044.
  14. Soerianto W, Jaspers I. E-cigarette, or Vaping, Product Use Associated Lung Injury: Epidemiology, Challenges, and Implications With COVID-19. Pediatr Pulmonol. 2025 Jan;60(1):e27448. doi: 10.1002/ppul.27448. PMID: 39714069.
  15. Despotes KA, Ceppe AS, Goralski JL, Donaldson SH. New era, new GOALs: cardiovascular screening and lipid management in cystic fibrosis. Ther Adv Respir Dis. 2025 Jan-Dec;19:17534666251317200. doi: 10.1177/17534666251317200. PMID: 39891563; PMCID: PMC11786282.