About
Spirovation is a non-profit translational CRO affiliated with the Marsico Lung Institute at the University of North Carolina at Chapel Hill, combining world-class academic scientific leadership with the operational capabilities of a contract research organization. We accelerate drug development in respiratory medicine, providing an efficient integration of academic expertise and industry business objectives.
The Marsico Lung Institute offers infrastructure with modern inter-disciplinary research units. Researchers assemble integrated project teams that dynamically respond to new knowledge, allowing early, iterative risk reduction through:
- Target ID & Validation
- Innovative animal models and in vitro models utilizing patient-derived materials
- Expertise in pathobiology of disease, enabling a pathway-based approach to target ID/ validation
- Biomarker identification/validation
- Resources, including the Sputum Core, for development of novel biomarkers for pulmonary drug development
- Early clinical trial design
- PK, target engagement, initial clinical benefit/ risk
Commitment to Customers
- Alignment of goals, incentives, processes and working practices
- Fast and easy contracting
- Integrated project management across labs
- High quality deliverables
- Cost effective
Scientific Leadership
- State-of-the-art research models, many unique
- Unrivaled expertise and resources in respiratory medicine
- Full cascade of mechanistic and functional studies from early screening through Phase IIa clinical trials, as well as Phase IV studies
- Publication record impacting respiratory science