Category: Research News
Removing the Penicillin Allergic Label: Researchers Introduce PADME
Doctors at the UNC School of Medicine, including Mildred Kwan, MD, PhD, and Cincinnati Children’s collaborate to develop an innovative, patient-initiated online platform designed to remove the penicillin allergy label from misdiagnosed pediatric patients. Here’s the scene. Your child appears to be sick. You take their temperature. Fever is over 100. Their throat hurts. You immedi … Read more
GIE Medical Announces First Patient Enrolled in PATENT-E Benign Esophageal Stricture Treatment Study
The large, multicenter randomized controlled clinical trial is evaluating the safety and efficacy of the ProTractX3™ TTS drug coated balloon for the treatment of benign esophageal strictures. News provided by GIE Medical via PRNewswire. MINNEAPOLIS – GIE Medical, a clinical stage company developing solutions for patients suffering from benign stricture(s) of the esophagus or bowe … Read more
Basch receives $3 million research award to launch national patient-reported outcomes project
The Patient-Centered Outcomes Research Institute (PCORI) has awarded UNC Lineberger’s Ethan Basch, MD, MSc, FASCO, $3 million in research funding to support a multi-institutional initiative to implement electronic patient-reported outcomes, or ePRO, in oncology practices across the country. “People being treated for cancer often experience a range of symptoms that can cause distr … Read more
Department of Medicine Grants & Funding: November 1 – November 30, 2023
Division of Hematology Rafal Pawlinski, PhD, and Brandi Reeves, MD, were awarded a one-year $75,000 UNC School of Medicine Phase 2 Translational Team Science Award (TTSA) for their project, “evaluating the role of hypoxia inducible factors in endothelial and hematopoietic cells in myeloproliferative neoplasms.” Division of Endocrinology & Metabolism Emily Pfaff, PhD, spoke ab … Read more
Novel study finds aspirin-free regimen benefits patients with LVAD
The ARIES-HM3 Randomized Clinical Trial assessed the safety and efficacy of excluding aspirin from the antithrombotic regimen in patients with advanced heart failure who have undergone implantation of a fully magnetically levitated left ventricular assist device (LVAD). “There has been no consensus in the field about use of or dose of aspirin in the LVAD population until this stu … Read more
Nelson Expresses Concern for Use of Methotrexate in Hand OA Following Clinical Trial
“Many individuals with hand OA have multiple medical comorbidities and polypharmacy, which are important when considering additional treatments, particularly those with modest benefit and potential adverse effects over the long term,” she said.
Department of Medicine Grants & Funding: October 1 – October 31, 2023
Division of Infectious Diseases Edward P Browne, PhD, received a: R61 grant from the NIDA to examine the impact of cannabinoids in HIV infected humanized mice. This is a five year, $3,465,157 grant. R21 grant from the NIAID to examine post therapy changes in CD4 T cells by single cell RNA sequencing. This award is $427,625. Nicholas Piazza, MD, received a $350,351 grant to intro … Read more
UNC Joins Osteoporosis Clinical Trial to Test Specialist-Fracture Liaison Service
Donald Caraccio, MD, principal investigator and assistant professor medicine, and Maya Styner, MD, associate professor of medicine, will lead a clinical site for the RESTORE study- REducing future fractureS and improving ouTcOmes of fRagility fracturE. Bones in patients with osteoporosis often become fragile and have an increased risk for fracture or break. Known as fragility … Read more
Researchers create a community resource referral program to address kidney health disparities
Drs. Gaurav Dave, associate professor of medicine, and Abhijit V. Kshirsagar, Covington Distinguished Professor of Medicine, received a grant from the NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to address structural racism to reduce kidney health disparities in rural North Carolina. North Carolina has the second largest rural population in the co … Read more
Dr. Boyce Receives $4.4 Million to Lead a Malaria Intervention Project in Uganda Following Extreme Weather Events
The NIH has awarded a multi-disciplinary team led by Ross Boyce, MD, MSc, a $4.4 million, five-year (R01) grant to evaluate the effectiveness of a chemoprevention effort designed to prevent malaria outbreaks after flooding, using a combination of interventions. Boyce is a member of the Institute for Global Health and Infectious Diseases (IGHID), an Assistant Professor in the Divi … Read more
Five NC Institutions Collaborating to Advance Kidney, Urology, Hematology (KUH) Research
Ronald Falk, MD, Nan and Hugh Cullman Eminent Professor of Medicine at UNC, Anthony Atala, MD, Professor of Medicine at Wake Forest University and Thomas Ortel, MD, PhD, Professor of Medicine at Duke University, will lead an effort to cultivate a highly skilled cohort of people and resources to advance research in kidney, urology, and hematology. Collaboration in medicine is comm … Read more
Gut Microbiome Can Increase Risk, Severity of HIV, EBV Disease
Angela Wahl, PhD, Balfour Sartor MD, and J. Victor Garcia, PhD, and colleagues created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and Epstein-Barr virus.