Faculty Experts

Spine Deformity Long-term results of surgical treatment of Scoliosis Progression of scoliosis and how to modify it Patient consequences of spine deformity Early Onset Scoliosis Childhood and adolescent growth and skeletal maturity of the spine and extremities Using quality improvement techniques to create better care

Our lab works on three interrelated subjects: (1) DNA Repair Enzymology and Genomics; (2) Mammalian Circadian Clock; (3) Control of DNA Repair by the Circadian Clock.

Our research focuses on the study of the dependent parvovirus adeno-associated virus. AAV is the only known DNA animal virus which requires co-infection by a second unrelated virus in order to undergo productive infection. The DNA tumor viruses, adenovirus and herpes simplex virus provide the necessary helper functions for AAV....

Dr. Rubinow is a Distinguished Professor of Psychiatry and Chair Emeritus at the University of North Carolina-Chapel Hill School of Medicine. Prior to being recruited to the University of North Carolina, he was Clinical Director of the National Institute of Mental Health (NIMH) and Chief of the Behavioral Endocrinology Branch...

Dr. Roy-Chaudhury currently leads a translational research program in uremic vascular biology funded through the National Institutes of Health, the Veterans Administration research program, and through industry grants. He has published over 175 papers, and is a sought after invited speaker, both nationally and internationally. He has also been actively...

Research Interests GPCR Structure and Function Synthetic Neurobiology Drug Discovery

The goal of my research career is to improve the quality of care and outcomes of patients with cancer by developing interventions to better align care delivery with what matters most to patients. I believe it is a fundamental obligation—a first principle of caring for patients—to make treatment decisions that...

Identification of airway epithelial stem cells. Dr. Randell’s goals are to identify and isolate airway epithelial stem cells and to understand molecular mechanisms regulating airway epithelial cell proliferation and fate decisions.Research in Dr. Randell’s laboratory is currently focused on five areas where a greater knowledge of basic cell biology can...

Mammals use three distinct pathways for repairing chromosome breaks. Ramsden lab is interested in the mechanistic details of how each pathway works, but also how and why a given pathway is chosen, and the consequences of choosing the “wrong” pathway. Ramsden lab’s work has relevance to normal organismal development and...

Our laboratory is interested in developing innovative approaches to regenerate or repair an injured heart. Our goal is to understand the molecular basis of cardiomyocyte specification and maturation and apply this knowledge to improve efficiency and clinical applicability of cellular reprogramming in heart disease. To achieve these goals, we utilize in vivo...

Understanding the molecular, cellular, and circuit-level basis for the pathophysiology underlying monogenic neurodevelopmental disorders.  A number of neurodevelopmental disorders are caused by mutations in different, seemingly unrelated, genes (e.g. – UBE3A and TCF4).  However, similar phenotypic manifestations suggest that these disorders share underlying cellular phenotypes, or give rise to perturbances that...

Breast cancer is a prevalent disease with known clinical and molecular diversity. To address these challenges, my research team uses a multidisciplinary approach based upon genomics, genetics, cancer biology, bioinformatics, epidemiology, and clinical research to improve the outcomes of cancer patients. A major contribution of mine has been the discovery...