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William Marston, MD

February 6, 2024
Endovascular surgery, limb preservation, wound care, vein disorders, dialysis access

David M Margolis, MD

February 6, 2024
David Margolis, MD is the director of the UNC HIV Cure Center, and a Sarah Grahm Keenan Distinguished Professor of Medicine, Microbiology & Immunology, and Epidemiology at the University of North Carolina at Chapel Hill. A graduate of Harvard College and Tufts University School of Medicine, he trained in medicine...

Tracy Manuck, MD, MS

February 6, 2024
Dr. Manuck is nationally renowned for her clinical and research work and specializes in providing care for women at highest risk for preterm birth, including those with cervical insufficiency, multiple previous preterm deliveries, and pre-viable preterm deliveries. Dr. Manuck also has expertise and passion for investigations of health disparities as...

Nigel Mackman, PhD

February 6, 2024
I am interested mechanisms of hemostasis and thrombosis, and the crosstalk between coagulation and inflammation. In particular, I study the role of tissue factor (TF), coagulation proteases, protease activated receptors (PARs) and microvesicles (MVs) in ischemia-reperfusion (I/R) injury, cancer, sickle cell disease, obesity, viral infection, atherosclerosis and liver injury. My...

Richard F. Loeser, Jr., MD

February 5, 2024
The Loeser lab uses a combination of in vitro studies in articular chondrocytes and in vivo studies in mice to examine molecular mechanisms of joint tissue destruction in aging and osteoarthritis. A major focus of this work is examining how reactive oxygen species regulate cell signaling through oxidation of Cys...

Chengwen Li, PhD

February 5, 2024
AAV vectors have been successfully applied in clinical trials in patients with eye and liver diseases. Several challenges limit AAV application including the capsid specific CTL response, AAV neutralizing antibody presence in human population, late innate immune response after AAV transduction and low transduction efficiency of AAV vector in humans....

Stan Lemon, MD

February 5, 2024
I have a longstanding interest in the mechanisms by which hepatotropic positive-strand RNA viruses replicate in the liver and cause diseases ranging from acute inflammatory hepatitis to cancer. My laboratory has focused on two viruses that are classified within different virus families, hepatitis A virus (HAV, a picornavirus) and hepatitis...

Helen Lazear, PhD

February 5, 2024
Flavivirus pathogenesis -Immune mechanisms that control Zika virus and other congenital infections -Zika virus infection in the female reproductive tract -Host genetic determinants of neuroinvasive flavivirus pathogenesis -Viral and host mechanisms that control flavivirus infection in the skin -Viral determinants of Zika virus replication and pathogenesis -No-known-vector flaviviruses IFN-λ mediated...

Matthew M. Laughon, MD, MPH

February 5, 2024
Dr. Laughon is a physician and researcher who specializes in neonatal and perinatal medicine. His research interests include neonatal epidemiology, neonatal clinical pharmacology trials (phase I, II, and III), and neonatal lung disease-particularly bronchopulmonary dysplasia (BPD). His research work integrates clinical efforts of neonatologists and pharmacologists from academic healthcare institutions...

Michael Kulis, PhD

February 5, 2024
Dr. Kulis is a biochemist whose work focuses on the development and mechanistic understanding of novel immunotherapy approaches for children with food allergies. He works closely with Drs. Wesley Burks and Edwin Kim as part of the UNC Food Allergy Initiative. Using animal models and human samples, Dr. Kulis and...

Abhijit V. Kshirsagar, MD, PhD

February 5, 2024
Chronic Kidney Disease; Cardiovascular Disease, Dialysis, Epidemiology, Anemia Management

Michael R. Knowles, MD

February 5, 2024
Genetic disorders of mucociliary clearance, including gene modifiers of disease phenotype in cystic fibrosis (CF) lung and liver disease, primary ciliary dyskinesia (PCD), as well as idiopathic bronchiectasis.