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Active Recruitment

Cornea Clinical Trials

Zoster Burden of Eye Disease/GSK (PI: Gower)
This is an observational, public health study in partnership with Rutgers University for patients with new or recurring herpes zoster.

Pediatric Clinical Trials

  1. Idiopathic Bilateral Cataracts/ Retrophin CTX Study (PI: Whitfield)
    This is a study looking at the relationship between idiopathic bilateral cataracts and the diagnosis of CTX.  Patients will be identified via chart review (or referral), and will have some labs done to test for the presence of CTX.  Study consists of one visit.
  2. ATS20: Binocular Dig Rush Game Treatment for Amblyopia
    This is a study for children ages 4 to 7 with amblyopia.  Subjects will be randomly assigned to either observation or to play a computer game 1 hour per day for at least 5 days a week.  The study will last for 16 weeks.  Those assigned to observation will have the option to switch to the computer game group after 8 weeks.
  3. ATS22: Pediatric Eye Disease Investigator Group (PEDIG) (PI: Whitfield)  
  4. Pediatric Myopia/Sydnexis STAAR Study (PI: Whitfield)
    This is a 4-year study testing low dose atropine to prevent progression of pediatric myopia.  Patients must be between the ages of 3 and 14, and meet certain vision criteria.

Studies In Progress

** No Longer Enrolling **

Retina Clinical Trials

Diabetic Retinopathy Clinical Research Network (DRCR) – PI: Ulrich

  1. DRCR AA
    Peripheral DR Lesions on Ultrawide-field Fundus Images and Risk of Diabetic Retinopathy
  2. DRCR AF
    A Randomized Trial Evaluating Fenofibrate for Prevention of Diabetic Retinopathy Worsening

    An observational study in partnership with Rutgers University for Herpes ZosterWorsening Over Time
    A four-year study that will be obtaining ultrawide imaging on patients with diabetic retinopathy.  Enrolled patients followed annually.
    An 18-month Observational Investigation of Patients with Open Angle Glaucoma and a Documented History of Visual Field Loss: Assessing the Reproducibility and Responsiveness of Outcome Measures of Glaucoma Progression.
  4. Improving African-American Patient Involvement in Visits and Outcomes
  5. ATS22
    A Randomized Trial to Evaluate Essential Versus Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old.
  6. Sydnexis STAAR
    A Randomized Trial of Low-Dose Atropine in Children Ages 3 to 14 to Prevent Progression of Myopia

No Active Studies


Completed Studies

  1. DRCR W: Intravitreous Anti-VEGF Treatment for Prevention of Vision Threatening Diabetic Retinopathy in Eyes at High Risk
    A four-year study looking at patients with Severe Non-Proliferative Diabetic Retinopathy (Severe NPDR).  Patients will be randomized to either study drug or sham injections to see if study drug injections help to prevent worsening of NPDR.  Participants will have best-corrected vision of 20/25 or better and not have any active diabetic macular edema, or any treatment for diabetic macular edema within the past year (including laser and injections).
  2. Treatment to Vision-Threatening Diabetic Retinopathy Patients in High-Risk Patients
  3. ROP3: Bevacizumab (0.063) for Infants with Type 1 Retinopathy of Prematurity (ROP)
  4. ROP4: Evaluate 0.063 mg vs. 0.025 mg Bevacizumab Treatment for Type 1 ROP, with ROP and Retinal Vessels All in Zone
  5. GSK 2140918: Characterization of Corneal Epithelial Changes in Participants Treated with Belantamab Mafodotin
  6. GSK2857916: A Companion Study
  7. HSC-MS-15-1053 – The AGS Second Aqueous Shunt Implant vs. TransScleral Cyclophotocoagulation Treatment Study (ASSISTS) (PI: Fleischman)
    Patients who have undergone previous glaucoma surgery, and require additional surgery.  The study will last for five years (follow-up will be the same as your standard of care visits).