Scientists Discover Intricacies of Serotonin Receptor Crucial for Better Therapeutics

August 31, 2018

By crystalizing a serotonin receptor bound to several common compounds, UNC School of Medicine scientists led by Bryan L. Roth discovered how slightly different drugs can cause severe side effects or none at all. The findings should accelerate the design of safer and more effective medications for a variety of conditions.

Nicholas Brown Earns MIRA from NIH

August 17, 2018

The National Institute of General Medical Sciences awarded Nicholas G. Brown $1.25 million over five years for research aimed at investigating the regulation of the enzyme known as the Anaphase-Promoting Complex/Cyclosome (APC/C) to ultimately understand cell cycle progression.

Discovery of kidney cancer driver could lead to new treatment strategy

July 19, 2018

In a study published in the journal Science, researchers led by UNC Lineberger’s Qing Zhang, Assistant Professor in the departments of Pathology & Laboratory Medicine and Pharmacology, suggest that ZHX2 is a potential new therapeutic target for clear cell renal cell carcinoma, which is the most common type of kidney cancer.

New genomic research on cardiovascular health in rural North Carolina

May 24, 2018

Two genomic-based studies from Heart Healthy Lenoir were published in the last month. Heart Healthy Lenoir was a multidisciplinary research project that aimed to reduce cardiovascular disease in Lenoir County, North Carolina by developing new approaches to care, from prevention to treatment. The lead investigator of the Heart Healthy Lenoir genomics study is Jonathan Schisler, PhD, assistant professor in the Department of Pharmacology and McAllister Heart Institute.