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Dr. Jenner successfully defended her thesis, “Kinase Inhibitor Therapies for Pancreatic Cancer” under the direction of her mentor, Dr. Jen Jen Yeh. 

Madison Jenner, PhD, at PhD thesis defense

Publications

Tumor-Intrinsic Kinome Landscape of Pancreatic Cancer Reveals New Therapeutic Approaches. Xu Y, Peng XL, East MP, McCabe IC, Stroman GC, Jenner MR, Chan PS, Morrison AB, Shen EC, Hererra SG, Joisa CU, Rashid NU, Iuga AC, Gomez SM, Miller-Phillips L, Boeck S, Heinemann V, Haas M, Ormanns S, Johnson GL, Yeh JJ. Cancer Discov. 2025 Feb 7;15(2):346-362. doi: 10.1158/2159-8290.CD-23-1480. PMID: 39632628. PMC11805639

Kinome state is predictive of cell viability in pancreatic cancer tumor and cancer-associated fibroblast cell lines. Berginski ME, Jenner MR, Joisa CU, Herrera Loeza G, Golitz BT, Lipner MB, Leary JR, Rashid N, Johnson GL, Yeh JJ, Gomez SM. PeerJ. 2024 Aug 28;12:e17797. doi: 10.7717/peerj.17797. eCollection 2024.
PMID: 39221276. PMC11365483

Integrated single-dose kinome profiling data is predictive of cancer cell line sensitivity to kinase inhibitors. Joisa CU, Chen KA, Berginski ME, Golitz BT, Jenner MR, Herrera Loeza G, Yeh JJ, Gomez SM. PeerJ. 2023 Nov 16;11:e16342. doi: 10.7717/peerj.16342. eCollection 2023. PMID: 38025707. PMC10657565

High-Field NMR Spectroscopy Reveals Aromaticity-Modulated Hydrogen Bonding in Heterocycles. Kakeshpour T, Bailey JP, Jenner MR, Howell DE, Staples RJ, Holmes D, Wu JI, Jackson JE. Angew Chem Int Ed Engl. 2017 Aug 7;56(33):9842-9846. doi: 10.1002/anie.201705023. Epub 2017 Jul 18. PMID: 28639283

Honors, Awards and Highlights

UNC Cancer Cell Biology Training Program Trainee

Dr. Jenner plans to continue her research as a Postdoctoral researcher in the Yeh Lab at UNC.

We wish you all the best, Maddy!