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Congratulations to Dr. Yinglong Miao for earning major media attention for his team’s groundbreaking study revealing, for the first time, how G-protein complexes detach from activated GPCRs—a key step in cell signaling.

Yinglong Miao, PhD
Yinglong Miao, PhD

Using advanced molecular simulations, the Miao Lab uncovered mechanisms that could guide the development of safer, more precise therapeutics.

Wang J, Nguyen ATN, Adediwura VA, Lu CS, McNeill SM, Jörg M, Scammells PJ, Christopoulos A, May LT, Miao Y. Dissociation kinetics of G proteins from G protein-coupled receptors and effects of allosteric modulation. Proc Natl Acad Sci U S A. 2025.

The study has already been featured on Phys.org and highlighted widely for its scientific importance. This recognition reflects the growing impact of Dr. Miao’s work in advancing computational biophysics and drug discovery.

Read the full press feature, “G protein simulations reveal how a critical signaling step works inside cells.”