Clinical Databases and Biorepositories
TARC Clinical Databases and Biorepositories
This table includes details for current clinical databases and biorepositories associated with TARC investigators. For anyone interested in learning more about the databases and biospecimens available or interested in collaborating on a project that utilizes the below resources, please reach out to the contact person listed for the study of interest.| Name of Study | PI Name(s) & Contact(s) | Clinical Variables | Biospecimens | Collection Timepoints | Enrolled Individuals |
|---|---|---|---|---|---|
| Total Knee Arthroplasty Database and Biorepository | Daniel Bracey, Richard Loeser, Joseph Hart Contact: Richard Loeser (Richard_Loeser@med.unc.edu) | - Demographics - Medications - Radiographs - Knee ROM - PROMIS-29 (pain, depression, anxiety) - KOOS (pain and function) - PCS (pain) | - Joint tissue (cartilage and synovial tissue) Planned: - Synovial fluid - Blood - Urine | Tissue and synovial fluid: - Time of surgery Blood and urine: - Time of surgery - 3mo - Post-surgery Radiographs: - Pre-op - 1, 2 and 5yrs post-surgery | Enrollment goal of 500 |
| LCCC 1937-Immuno-Oncology Database: Identifying Mechanisms of Autoimmune Diseases in the Era of Cancer Immunotherapy | Rumey Ishizawar Contact(s): Shivani Surati (Shivani_Surati@med.unc.edu) Shruti Saxena Beem (shruti_saxena@med.unc.edu) | - General health - Medications - Allergies - Comorbidities - Autoimmune conditions - Demographics - Socioeconomic status - Quality of Life - Cancer diagnosis, treatment, and history - Immune-related adverse events | - DNA from cheek swab - Blood serum - PBMCs - Whole urine - Urine supernatant and pellet - Feces for microbiome | - Baseline - Every 12wks until 2yrs after ICI therapy | Enrollment goal of 200 - 24 currently enrolled |
| Alpha-gal Allergy | Scott Commins Contact: Scott Commins (scommins@email.unc.edu) | - Allergic or not allergic | - Plasma - Sera - PBMCs | 2020-2023 | Approx. 400 enrolled |
| Identification of Causes and Markers of Renal Disease | Ronald Falk Contact: Lauren Blazek (lmccabe@email.unc.edu) | - Treatment - Outcomes - Histopathology | - Blood - Urine - Stool | - Once/yr from participants with glomerular disease (varies depending on cohort) | 3,000 enrolled |
| Longitudinal ACL Injury Database | Brian Pietrosimone Contact: Brian Pietrosimone (pietrosi@email.unc.edu) | - Biomechanics - Knee joint MRI - Patient reported outcomes (KOOS, IKDC, Kinesiophobia) | - Synovial fluid - Serum - Plasma - Urine | - Preoperative - Time of ACL reconstruction - 2, 4, 6, and 12mo post-ACL reconstruction | 60 enrolled |
| The Johnston County Health Study | Amanda Nelson Contact: Patrick Gale (w.patrick.gale@unc.edu) | - General health - Medications - Allergies - Comorbidities - Autoimmune conditions - Demographics - Socioeconomic status - Radiographs - Ultrasounds | - Serum - Plasma - Urine - White cells | 2019 - ongoing | 806 enrolled |
This table was updated on 02/08/2024.