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Events at this venue

Today

  • TARC Research Seminar: Dr. Ming-Feng Hsueh; “Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis”

    Remote or In Person Options Available

    "Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis" Brief Description: Through the novel use of in vivo protein deamidation molecular clocks, we unmasked a position-dependent gradient of protein anabolism in human lower limb cartilages. This gradient is strikingly associated with the expression of evolutionarily-conserved limb-regenerative miRNAs. This association shows a potential link to a capacity … Read more

  • TARC Research Seminar: Dr. Anne-Marie Malfait; “Neuroplasticity in the knee joint: More than just pain.”

    Remote or In Person Options Available

    "Neuroplasticity in the knee joint: More than just pain." Brief Description: I will describe the sensory innervation of the joint, its anatomical and molecular properties, and how these properties change in the course of osteoarthritis (=neuroplasticity). I will discuss the biological role of this neuroplasticity in pain and in joint homeostasis. Anne-Marie Malfait, MD, PhD … Read more

  • Rheumatology, Allergy & Immunology Grand Rounds: Dr. Terrence Holt; “Is Narrative Medicine?”

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    Dr. Terrence Holt Assistant Professor of Social Medicine and Internal Medicine Division of Geriatric Medicine, UNC *VIRTUAL ATTENDANCE ONLY FOR THIS PRESENTATION*  Join Zoom Meeting https://zoom.us/j/93369235083?pwd=TU9GQ2dsMitLVk96VjZSV3N4OHpYdz09 Meeting ID: 933 6923 5083 Passcode: 363826 One tap mobile +13126266799,,93369235083#,,,,*363826# US (Chicago) +16465588656,,93369235083#,,,,*363826# US (New York) This activity has been planned and implemented under the sole supervision of the … Read more

  • TARC Research Seminar: Dr. Brian Diekman; “DNA Damage and Cellular Senescence in Osteoarthritis Pathophysiology.”

    Remote or In Person Options Available

    "DNA damage and cellular senescence in osteoarthritis pathophysiology.” Brief Description: Aging is the largest risk factor for osteoarthritis, but the mechanisms responsible for this relationship are unclear. Damaged cells can convert to a phenotypic state known as cellular senescence, and senescent cells are associated with compromised tissue function. This talk will focus on our efforts … Read more

  • TARC Research Seminar: Dr. Janet Rubin; “The Skeleton in a Physical World”

    Remote or In Person Options Available

    "The Skeleton in a Physical World" Brief Description: All organisms exist within a physical space and respond to physical forces as part of daily life. The skeleton responds in real-time to physical stresses placed on it to ensure that its structure supports its function. I will discuss how those cells responsible for remodeling skeletal structure … Read more

  • Annual “TARC Research Day,” Being Held In-Person, With Remote Options

    Remote or In Person Options Available

    After two years of meeting virtually, we are excited to once again host Research Day 2022 in person.* *(In-person attendance pending potential changes in University policies due to COVID-19.) All presenters will host their sessions in person. For certain events there will be a virtual/Zoom option, for attendees unable to attend in person. Be sure … Read more

  • TARC Research Seminar: Dr. Laurie Goodrich; “Orthopedic Translational Medicine: Horses, Humans and the Pursuit of Joint Health”

    Remote or In Person Options Available

    Presentation Title: "Orthopedic Translational Medicine: Horses, Humans and the Pursuit of Joint Health" Brief description: Post-traumatic Osteoarthritis (PTOA) is extremely common in equine athletes as well as humans. The horse is an incredible translational model and has been utilized for decades to inform equine clinicians treating their patients and MD’s treating people with PTOA. Further, … Read more

  • TARC Research Seminar: Dr. Doug Phanstiel; “Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis”

    Remote or In Person Options Available

    "Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis" Genome-wide association studies (GWAS) have identified over 100 osteoarthritis (OA)-associated loci; however, translating these broad loci into actionable therapeutic targets requires identifying the causal variants, the gene(s) they affect, and their mechanistic impact on OA risk. We apply genomic, bioinformatics, and genome editing approaches to identify … Read more

  • TARC Research Seminar: Dr. Raghunatha Yammani; “Proteostasis: Does it have a role in osteoarthritis?”

    Remote or In Person Options Available

    Proteostasis: Does it have a role in osteoarthritis? Brief description: Loss of proteostasis is one of the hallmarks of aging. We found that aging reduces the expression of molecular chaperones in chondrocytes resulting in cellular stress and inflammation, which could contribute to the development of osteoarthritis. Dr. Raghunatha Yammani Associate Professor, Molecular Medicine Wake Forest … Read more

  • TARC Research Seminar: Dr. Lauren Schnabel; “A new approach to infectious arthritis: understanding bacterial behavior in synovial fluid and developing a novel therapeutic”

    Remote or In Person Options Available

    "A new approach to infectious arthritis: understanding bacterial behavior in synovial fluid and developing a novel therapeutic" Brief Description: This seminar will highlight our group's work on how and why bacteria form free-floating biofilms in synovial fluid including our ex-vivo model system. The seminar will then focus on our development of a novel therapeutic, BIO-PLY, … Read more