KATHRYN GUNN, PHD ǀ University of North Carolina-CH Lab: Saskia Neher “Catching a Glimpse of Lipoprotein Lipase” Lipoprotein Lipase (LPL) is a key enzyme for regulation of triglyceride levels in the blood. My research seeks to uncover new details about how the structure of LPL informs its regulation and function.
BING ZHANG, PHD ǀ Baylor College of Medicine Host: Xian Chen “Proteogenomics: A New Avenue for Cancer Research” Proteogenomics is a new research field at the interface of genomics and proteomics. In this talk, I will introduce our computational infrastructure and bioinformatics tools for cancer proteogenomic data analysis. Using proteogenomics data from the Clinical … Read more
UNC BIOCHEMISTRY & BIOPHYSICS GRADUATE STUDENT INVITED LECTURE JOSEPH COTRUVO, PHD ǀ Penn State University “Selective recognition of lanthanides in biology” Listen to 11/5 Science Seminar Podcast
WENTAO LI, PHD Lab: Sancar Seminar title, “Mapping the Hotspots and Coldspots of Nucleotide Excision Repair and DNA Damage Formation” Abstract: The level of DNA damage formation and the efficiency of repair are of primary importance because they determine the ultimate DNA damage frequency and its persistence in the genome, which … Read more
The Biochemistry and Biophysics department will gather at the Genetic Medicine Building third floor for a potluck feast. Come bring a dish and network with other members on Friday, November 15th, 2019. If you are a team member or a collaborator and work in another building - please come over and join us at this … Read more
KATE MEYER, PHD ǀ Duke University School of Medicine Host: Bill Marzluff ““Detecting RNA methylation and its role in gene expression” Abstract: N6-methyladenosine (m6A) is a highly prevalent RNA modification which controls nearly every aspect of the mRNA life cycle. Recent improvements in m6A mapping methods have significantly advanced our understanding of m6A distribution … Read more
DANIEL DOMINGUEZ, PHD ǀ University of North Carolina--CH Host: Brian Strahl “RNA Binding and Regulation in Normal and Disease States"
Join us for our annual holiday party and Awards Presentation. There will be a sit-down dinner, raffle door prizes and gingerbread house decorating contest.
“Selective ER-Export of Misfolded Secretory Pathway Proteins for Lysosomal Degradation” Host: Sasky Neher ABSTRACT We discovered that a subset of misfolded secretory pathway proteins, including variants of prion protein and amyloid precursor protein, are selectively exported out of the ER by a constitutive and stress-enhanced pathway named RESET. After RESET, these misfolded proteins are subsequently … Read more
David Peden, MD, MS Harry S. Andrews Distinguished Professor Pediatrics, UNC-CH School of Medicine Host: Leslie Parise “Inflammatory Response to Air Pollutants in Humans” Abstract: Air pollution is a common threat to public health. A common response to a number of pollutants is inflammation, which is reflected in a variety of acute pathophysiologic conditions. … Read more
