Seminar title “A Novel Targeted Nanotherapeutic Approach to Stop Hemorrhage” Host: Leslie Parise Dr. Melina Kibbe is the Colin G Thomas Distinguished Professor and Chair of Surgery at UNC who moved here almost 3 years ago from Northwestern University. She is a very engaging speaker whose research encompasses various aspects of blood vessel growth and … Read more
Department public service volunteer opportunity at Carolina Community Garden July 16, 3-5pm. No gardening knowledge necessary. The garden supplies fresh vegetables to low-income employees. More details will be forthcoming. Organizer: Lisa Phillippie
DAVID FRUMAN, PHD ǀ University of California- Irvine Host: Pengda Liu “Strategies to target the mTORC1/eIF4F Axis in B-cell malignancies” Abstract: mTOR complex-1 (mTORC1) is a key regulator of B cell proliferation and differentiation. Elevated mTORC1 activity is also common in B cell cancers and is associated with poor prognosis. We have shown that … Read more
EDWARD EGELMAN, PHD ǀ University of Virginia Host: Saskia Neher “Cryo-EM of Helical Polymers at Near-Atomic Resolution Yields Many Surprises”
LARISA LITOVCHICK, PHD ǀ Virginia Commonwealth University Host: Jean Cook “Regulation of Cellular Quiescence” ABSTRACT: Quiescence is defined as non-proliferative state of cells that the retain ability to re-enter the cell cycle. Entry into quiescence is mediated by phosphorylation-dependent protein complexes that include retinoblastoma family proteins. This presentation will review the mechanisms by which entry … Read more
JONATHAN BERG, MD, PHD ǀ University of North Carolina- CH Host: Leslie Parise Seminar Title, “Advancing the science of clinical variant interpretation using validated functional assays”
JIMENA GIUDICE, PHD ǀ University of North Carolina- CH Host: Saskia Neher “Alternative splicing and membrane trafficking in development and disease” Abstract: Black AJ*, Blue RE*, Engels NM1, Wiedner HJ, Hinkle ER, Giudice J The University of North Carolina at Chapel Hill. *equal contribution Alternative splicing is a posttranscriptional mechanism that produces multiple protein … Read more
GABE LANDER, PHD, Professor, Department of Integrative Structural and Computational Biology, Scripps Research Institute Host: Rob McGinty “The highs and lows of cryo-EM and its use in studying molecular machines of mass destruction” Abstract:Technical and methodological advances in single-particle cryo-electron microscopy (cryo-EM) have expanded the technique into a resolution regime that was previously only attainable by X-ray crystallography. … Read more
Schedule of Events Registration Call for Abstracts
HEIDI HAMM, PHD ǀ Vanderbilt University Host: Judith Bond “Regulation of Exocytosis by inhibitory GPCRs and Gbg subunits”
