Read full article This paper, which was first-authored by former graduate trainee James Byrnes, investigated the relationship between coagulation factor XIII A and B subunits in circulation. Although these subunits are produced in different tissues, their data reveal a unique reciprocal regulatory mechanism in which each subunit determines the circulating half-life of the other subunit. This kind of regulatory mechanism has not been previously reported in a plasma protein. The paper was accompanied by an editorial by Dr. Nathan Connell. Read article here