April 15, 2026
David Paul, PhD (Assistant Professor) and David Rocco (graduate student, Cell Biology and Physiology) from the Bergmeier lab publish co-first author paper in Blood describing a new signaling pathway critical for platelet adhesion under arterial shear conditions. The findings of this study markedly improve our understanding of G protein signaling and integrin function in platelets, …
April 6, 2026
Dr. Matthew Flick received an award from Glycos Biomedical Ltd. for his work entitled “GBM-1511 as Adjunctive Sepsis Therapeutic for Staphylococcus Aureus and Streptococcus Pneumonia”. Congratulations Dr. Flick!
April 6, 2026
Steve Hur, PhD was selected to receive a Career Development Award from the American Heart Association totaling $77,000 every year for the next three years. Congratulations Dr. Hur!
April 6, 2026
Dr. Erica Sparkenbaugh was awarded the UNC School of Medicine Office of Research Translational Team Science Award (TTSA) pilot grant for her application titled “Hypoxemia-Induced Platelet Activation in Sickle Cell Disease Pregnancy: Mechanisms and Therapeutic Targets”. The team includes Drs. Erica Sparkenbaugh and Mofiyin Obadina from the Department of Medicine. Congratulations Dr. Sparkenbaugh!
March 16, 2026
Bergmeier proposal receives NIH/NHLBI R35 Outstanding Investigator Award. The award is intended to “promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Principal Investigators … whose outstanding record of research demonstrate their ability to make major contributions to the heart, lung, blood and sleep (HLBS) research.” Lead PI: Wolfgang Bergmeier Proposal …
March 10, 2026
Abigail Ballard-Kordeliski, former graduate student and member of Bergmeier lab, published paper in Haematologica. Paper describes new mechanistic findings on role of small G proteins in platelet pro-coagulant response. https://pubmed.ncbi.nlm.nih.gov/41784022/
March 10, 2026
Robert H. Lee, PhD, Wolfgang Bergmeier, PhD, Matthew J. Flick, PhD and Steve Hur, PhD, published collaborative paper in Blood, 1st author is Robert Lee – senior author is Steve Hur (Pathology). Paper describes new findings on the role of fibrinogen aC-region in arterial thrombosis in hypofibrinogenemic conditions, establishing a link to platelets via the …
March 10, 2026
Kadri Kangro, Samer Issa, Alisa Wolberg and Matthew Flick authored “SARS-CoV-2 spike protein can bind fibrin(ogen), but does not alter plasma fibrin formation, clot structure, or lysis” Link to publication
March 6, 2026
Stephan Moll, MD, UNC BRC member, and Steven Grover, PhD, former BRC member, are coinvestigators on a 5-year NASA study called ‘Venous Flow’ that studies the risk of venous thromboembolism (VTE) in zero gravity [ref 1]. The past finding of a jugular deep vein thrombosis (DVT) in an astronaut on the International Space Station …
March 6, 2026
Mofiyin Obadina, MD and Erica Sparkenbaugh, PhD received funding from NC TRaCS for their TTSA proposal entitled “Hypoxemia-Induced Platelet Activation in Sickle Cell Disease Pregnancy: Mechanisms and Therapeutic Targets.” This award supports the development of new interdisciplinary collaborations and projects. Here, Dr. Obadina and Dr. Sparkenbaugh will explore the effect of nocturnal hypoxemia on aberrant …
March 2, 2026
Drs. Steven Hur and Matthew Flick recently had their work “Urokinase Plasminogen Activator Deficiency Delays the Development of Obseity and Metabolic Sequelae” published in Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB). Read more here
February 17, 2026
Dr. Ramadas and Sparkenbaugh recently published their study “Targeting PAR1 Biased Signaling with Parmodulin Reduces Thromboinflammation and Acute Lung Injury in Sickle Cell Disease” in Blood Advances. UNC BRC undergraduate alumni Joshua Dutton and Kailyn Lowder are co-authors. Drs Rani Sellers and Claire Kazen performed veterinary histopathology. Drs. Jacob DeRousse and Chris Dockendorff provided reagents. …