September 10, 2024
Abby Kordeliski has had the final version of her paper “4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model” published in Blood along with the cover image. Abby works in the Wolfgang Bergmeier laboratory in Mary Ellen Jones Building, Congratulations Abby! Cover image Link to the article that …
July 18, 2024
“Blood coagulation factor IX: structural insights impacting hemophilia B therapy” was recently accepted for publication in the journal Blood. The work is a collaboration between BRC Center member Dougald Monroe and Leiden University Medical Center investigators Rianne Elaine van Diest and Mettine H A Bos. This review focuses on analyzing the structure of factor IX …
May 23, 2024
Steven Grover, PhD received the 2024 Kenneth M. Brinkhous Early Career Investigator Prize in Thrombosis at the American Heart Association Vascular Discovery meeting. At the meeting Dr. Grover presented his groups recent research on the role of plasma kallikrein as a key driver of coagulation under conditions of C1-inhibitor deficiency. The Kenneth M. Brinkhous Prize recognizes outstanding …
May 22, 2024
Congratulations to Linda Sundler Björkman MD, PhD, currently a postdoctoral fellow in the lab of Steven Grover, PhD, whose article “Increased risk of venous thromboembolism in young and middle-aged individuals with hereditary angioedema: a family study” has been accepted for publication in the journal Blood! This work, conducted in collaboration with colleagues from Lund University, …
May 21, 2024
Dr. Stephan Moll coauthored an article published on May 15, 2024 in the New England Journal of Medicine (https://www.nejm.org/doi/full/10.1056/NEJMc240259 ) expanding on an earlier observation (Warkentin TE et al. https://www.nejm.org/doi/full/10.1056/NEJMc2307721 ) that adenoviral infection can be associated with a clinical picture of severe thrombosis and thrombocytopenia, triggered by antibody formation against platelet factor 4 (PF4), …
May 7, 2024
The International Society of Thrombosis and Haemostasis (ISTH) announces Alisa Wolberg, PhD as one of the recipients of its inaugural Outstanding Mentor Award for 2024. The Outstanding Mentor Awards are a new award from the ISTH in 2024, recognizing individuals who have demonstrated an ongoing commitment to cultivate and mentor early career professionals in the …
April 22, 2024
Drs. Ramadas, Trebak, Pawlinski and Sparkenbaugh are co-authors of “Biased agonism of protease-activated receptor-1 regulates thrombo-inflammation in murine sickle cell disease” and their manuscript was accepted in Blood Advances. In this study, they showed that APC inhibition exacerbates thrombin generation, inflammation and end-organ damage in a mouse model of sickle cell disease (SCD), and that APC-PAR1 …
April 3, 2024
Drs. Hisada, Key, and Mackman are co-authors of “Biomarkers of bleeding and venous thromboembolism in patients with acute leukemia” and their manuscript was accepted by The Journal of Thrombosis and Haemostasis. In this manuscript, they showed that increased extracellular vesicle tissue factor activity is associated with bleeding whereas increased plasminogen activator inhibitor-1 levels are associated …
March 25, 2024
2024 Biology Undergraduate Honors Research Symposium – Coag and Fibrinolysis On Wednesday, April 3, 2024 from 2:00-3:30pm, Yesha Patel, Olivia White, and Sophia Dhrolia will be presenting their research in Coker Hall, Room 215. See the attached flyer for details.
March 5, 2024
Dr. Melissa Caughey and Dr. Matt Karafin was awarded a 3-year R21 grant for the NIBIB Trailblazer Award for Early Stage Investigators titled “Development of a contact-free assay to evaluate stored blood quality using ultrasound viscoelasticity techniques”.