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Nature Cardiovascular Medicine publication written with our Duke colleague Dr. Ammon Fager. Title – Stopping the bleed when platelets don’t stick Journal – Nature Cardiovascular Research DOI – 10.1038/s44161-024-00421-3 View and download PDF

New MPI R01 awarded in the amount of $720,846 from the NIH National Heart, Lung, and Blood Institute (NHLBI) project title: Mechanisms of venous thrombosis and renal dysfunction in sickle trait. Abstract: This proposal will use both human blood samples from subjects who are carriers of the sickle cell gene...

The Junior Faculty Development Awards are funded by IBM and R.J. Reynolds Industries, Inc.  This award grants $10,000 to support scholarly pursuits over one calendar year. JUNIOR FACULTY DEVELOPMENT AWARDS FOR 2024 UNC Faculty Award Announcement

In the recently published work in Proceedings of the National Academy of Sciences (PNAS), Dr. Antoniak’s and Dr. Mackman’s groups from the UNC Blood Research Center show that SARS-CoV-2 encodes antimicrobial peptides (xenoAMPs) which can form proinflammatory complexes. These complexes induced a proinflammatory and procoagulant phenotype  in cells in vitro...

Read full article This paper, which was first-authored by former graduate trainee James Byrnes, investigated the relationship between coagulation factor XIII A and B subunits in circulation. Although these subunits are produced in different tissues, their data reveal a unique reciprocal regulatory mechanism in which each subunit determines the circulating...

Myocarditis Foundation Awards 2023 Fellowship Grant Myocarditis Foundation proudly awards 2023 Fellowship Grant to Dr. Swati Sharma of University of North Carolina, Chapel Hill One of the 2023 Fellowship Grants was awarded to Dr. Swati Sharma, for her work on: “The Protective Role of Platelet Protease-activated Receptor4 (PAR4) in Coxsackievirus (CVB3)...

Dr. Yohei Hisada has been appointed as an Early Career Editorial Board member of ATVB. He will serve for two years, from January 2024 to December 2025. ATVB site

View January 2024 Newsletter

Dr. Dre’Von Dobson, former graduate student in Dr. Alisa Wolberg’s laboratory received a 2024 JTH Editors Award for his paper entitled, “Novel Genetic Regulators of Fibrinogen Synthesis Identified by an In Vitro Experimental Platform” published in the Journal of Thrombosis and Haemostasis in 2023. Link to article: JTH  

Paper published in Blood documenting how a nonpolymerizable fibrinogen can protect against thrombosis without compromising hemostasis. This work was featured on the cover and designated a Plenary Paper by the journal. An image of the cover is attached. Here is a link to the article: https://ashpublications.org/blood/article-abstract/143/2/105/498325/Mice-expressing-nonpolymerizable-fibrinogen-have?redirectedFrom=fulltext. The lead author on this...

Project Title: Evaluation of a C1 inhibitor variant as a novel hemostasis sparing anticoagulant Awardee: Ana Sachetto Mentor: Nigel Mackman Co-mentor: Steven Grover Total amount awarded: $151,564

The 17th Annual Earl W. Davie Symposium November 16, 2023 Dr. Alisa Wolberg presented a Keynote Address entitled, “Exploring the determinants of clot formation in thrombosis and bleeding” at the 2023 Earl Davie Symposium in Vancouver, BC. Website: 2023 Earl Davie Symposium