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David B. Peden, MD

Distinguished Professor of Pediatrics

 

Dr. David B. Peden is the Harry S. Andrews Professor of Pediatrics, Medicine and Microbiology/Immunology as serves as the Senior Associate Dean for Translational Research, Immunology and Rheumatology, and Associate Director, Center for Environmental Medicine, Asthma & Lung Biology for the UNC School of Medicine (SOM). He also has secondary appointments in the Departments of Epidemiology and Environmental Science & Engineering in the Gillings School of Global Public Health (SPH) and the Department of Surgery in the SOM.  Dr. Peden received his Doctor of Medicine and Master of Science in Pharmacology and Toxicology degrees from West Virginia University and completed his residency and chief residency in Pediatrics at West Virginia University Medical Center. His fellowship training in allergy and immunology was completed at the National Institutes of Health’s National Institute of Allergy and Infectious Diseases in Bethesda, Maryland.

 

In the clinic: Dr. Peden is board certified in pediatrics, allergy and immunology and clinical laboratory immunology. He sees patients with a wide range of allergic and immunologic disorders at the UNC Pediatric Allergy and Immunology Clinic at the North Carolina Children’s Hospital.

 

Clinical Awards/Honors: President, American Academy of Allergy, Asthma and Immunology, 2017-2018

Presidential Track Offices: Secretary/Treasurer, 2015-2016; President Elect, 2016-2017, President, 2017-2018; Past President, 2018-2019. US News and World Report Top Doctors for Allergy and Immunology, 2012 – date, Best Doctors listing for Allergy and Immunology, 2007-date

 

Research: Dr. Peden’s group has extensive expertise in evaluating persons for asthma, allergies and lung disease, using spirometry, methacholine challenge, analysis of induced sputum and allergen skin testing.

Dr. Peden is currently principal investigator for over $5 million of federally grant funded research from EPA, NCATS, NIAID, NIEHS, NHLBI and NSF. These studies include a number of clinical investigations examining the effect of challenge and exposure to a number of environmental agents, including ozone, endotoxin, concentrated air particulates and woodsmoke particles. His current projects include assessing the effect of gamma tocopherol on the effect of ozone and wood smoke in heathy and asthmatic volunteers, phase I/II studies focused on novel treatments for airway clearance in asthma in conjunction with the Marsico Lung Institute.

 

He also serves as a member of the Executive and Steering Committees for the NHLBI PreCISE program for testing precision medicine approaches for novel agents in asthma as part of the UNC team from the Collaborative Studies Coordinating Center from the SPH, as a key investigator in the NCATS-funded Biomedical Data Translator program in conjunction with RENCI and is site PI for the NIAID funded Immune Tolerance Network study CATNIP, which examines the effect of anti-TSLP on response to cat allergic persons to cat immunotherapy. He is also Medical Director of the NSF Nanosystems Engineering Research Center for Advanced Self-Sustaining Integrated Sensor Technologies (ASSIST) based at NCSU, which is focused on developed and testing wearable sensors for physiologic and environmental exposure data.

 

Public Service: Dr. Peden is regularly serves on NIH grant review committees, as is a regular member of EPA advisory committees for Sulfur Oxides and Particulate matter and is the Chair of the FDA Allergenic Products Advisory Committee. He also serves as an Associate Editor for the Journal of Allergy and Clinical Immunology and is Editor-in-Chief of Current Allergy and Asthma Reports.

 

Collaborative Projects/Research Interests

 

  1. Pollution and environmental factors in allergic disease and asthma

 

  1. Evaluation of novel therapeutic agents for asthma, allergies and airway disorders

 

  1. Airway antioxidant and oxidant physiology

 

  1. Granulocyte function in airway disease