Department of Genetics Publications for February 12th – 25th, 2023

Department of Genetics faculty, postdocs, students and collaborators published 9 papers during February 12^th – 25^th, 2023.

 

Translating transcriptomic findings from cancer model systems to humans through joint dimension reduction. 

Price BA, Marron JS, Mose LE, Perou CM, Parker JS.

Commun Biol. 2023 Feb 16;6(1):179. doi: 10.1038/s42003-023-04529-3.

PMID: 36797360

 

Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits. 

Westerman KE, Walker ME, Gaynor SM, Wesse J, DiCorpo D, Ma J, Alonso A, Aslibekyan S, Baldridge AS, Bertoni AG, Biggs ML, Brody JA, Chen YI, Dupuis J, Goodarzi MO, Guo X, Hasbani NR, Heath A, Hidalgo B, Irvin MR, Johnson WC, Kalyani RR, Lange L, Lemaitre RN, Liu CT, Liu S, Moon JY, Nassir R, Pankow JS, Pettinger M, Raffield L, Rasmussen-Torvik LJ, Selvin E, Senn MK, Shadyab AH, Smith AV, Smith NL, Steffen L, Talegakwar S, Taylor KD, Vries PS, Wilson JG, Wood AC, Yanek LR, Yao J, Zheng Y, Boerwinkle E, Morrison AC, Fornage M, Russell TP, Psaty BM, Levy D, Heard-Costa NL, Ramachandran VS, Mathias RA, Arnett DK, Kaplan R, North KE, Correa A, Carson A, Rotter JI, Rich SS, Manson JE, Reiner AP, Kooperberg C, Florez JC, Meigs JB, Merino J, Tobias DK, Chen H, Manning AK.

Diabetes. 2023 Feb 15:db220851. doi: 10.2337/db22-0851. Online ahead of print.

PMID: 36791419

 

MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing. 

Vital T, Wali A, Butler KV, Xiong Y, Foster JP 2nd, Marcel SS, McFadden AW, Nguyen VU, Bailey BM, Lamb KN, James LI, Frye SV, Mosely AL, Jin J, Pattenden SG, Davis IJ.

Front Oncol. 2023 Jan 30;13:1099550. doi: 10.3389/fonc.2023.1099550. eCollection 2023.

PMID: 36793594 Free PMC article.

 

Physical activity and diet associations with the gut microbiota in the Coronary Artery Risk Development in Young Adults (CARDIA) study. 

Memili A, Lulla A, Liu H, Shikany JM, Jacobs DR Jr, Langsetmo L, North KE, Jones C, Launer LJ, Meyer KA.

J Nutr. 2022 Dec 26:S0022-3166(22)13264-5. doi: 10.1016/j.tjnut.2022.12.019. Online ahead of print.

PMID: 36775672

 

Insulin Elevates ID2 Expression in Trophoblasts and Aggravates Preeclampsia in Obese ASB4-Null Mice. 

Kayashima Y, Townley-Tilson WHD, Vora NL, Boggess K, Homeister JW, Maeda-Smithies N, Li F.

Int J Mol Sci. 2023 Jan 21;24(3):2149. doi: 10.3390/ijms24032149.

PMID: 36768469 Free PMC article.

 

Prenatal phenotype of 47, XXY (Klinefelter syndrome). 

Swanson K, Bishop JC, Al-Kouatly HB, Makhamreh M, Felton T, Vora NL, Sparks TN, Jelin AC.

Prenat Diagn. 2023 Feb;43(2):207-212. doi: 10.1002/pd.6071. Epub 2021 Dec 7.

PMID: 34874073 Review.

 

DNAmFitAge: biological age indicator incorporating physical fitness. 

McGreevy KM, Radak Z, Torma F, Jokai M, Lu AT, Belsky DW, Binder A, Marioni RE, Ferrucci L, Pośpiech E, Branicki W, Ossowski A, Sitek A, Spólnicka M, Raffield LM, Reiner AP, Cox S, Kobor M, Corcoran DL, Horvath S.

Aging (Albany NY). 2023 Feb 22;15. doi: 10.18632/aging.204538. Online ahead of print.

PMID: 36812475

 

Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements. 

Snouwaert JN, Jania LA, Nguyen T, Martinez DR, Schäfer A, Catanzaro NJ, Gully KL, Baric RS, Heise M, Ferris MT, Anderson E, Pressey K, Dillard JA, Taft-Benz S, Baxter VK, Ting JP, Koller BH.

PLoS Pathog. 2023 Feb 22;19(2):e1011168. doi: 10.1371/journal.ppat.1011168. Online ahead of print.

PMID: 36812267

 

Diagnosis of TBC1D32-associated conditions: Expanding the phenotypic spectrum of a complex ciliopathy. 

Harris SC, Chong K, Chitayat D, Gilmore KL, Jorge AAL, Freire BL, Lerario A, Shannon P, Cope H, Gallentine WB, Le Guyader G, Bilan F, Létard P, Davis EE, Vora NL.

Am J Med Genet A. 2023 Feb 24. doi: 10.1002/ajmg.a.63150. Online ahead of print.

PMID: 36826837