Department of Genetics faculty, postdocs, students and collaborators published twelve papers during July 12-25, 2020.

 

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.
Hagenaars SP, Coleman JRI, Choi SW, Gaspar H, Adams MJ, Howard DM, Hodgson K, Traylor M, Air TM, Andlauer TFM, Arolt V, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Campbell A, Cearns M, Czamara D, Dannlowski U, Domschke K, de Geus EJC, Hamilton SP, Hayward C, Hickie IB, Hottenga JJ, Ising M, Jones I, Jones L, Kutalik Z, Lucae S, Martin NG, Milaneschi Y, Mueller-Myhsok B, Owen MJ, Padmanabhan S, Penninx BWJH, Pistis G, Porteous DJ, Preisig M, Ripke S, Shyn SI, Sullivan PF, Whitfield JB, Wray NR, McIntosh AM, Deary IJ, Breen G, Lewis CM.
Am J Med Genet B Neuropsychiatr Genet. 2020 Jul 18. doi: 10.1002/ajmg.b.32807. [Epub ahead of print]
PMID: 32681593

 

Autophagy regulates the localization and degradation of p16<sup>INK4a</sup>.
Coryell PR, Goraya SK, Griffin KA, Redick MA, Sisk SR, Purvis JE.
Aging Cell. 2020 Jul 13:e13171. doi: 10.1111/acel.13171. [Epub ahead of print]
PMID: 32662244

 

Expression of UDP Glucuronosyltransferases <i>2B15</i> and <i>2B17</i> Is Associated with Methylation Status in Prostate Cancer cells.
Shafiee-Kermani F, Carney ST, Jima D, Utin UC, Farrar LB, Oputa MO, Hines MR, Kinyamu HK, Trotter KW, Archer TK, Hoyo C, Koller BH, Freedland SJ, Grant DJ.
Epigenetics. 2020 Jul 13. doi: 10.1080/15592294.2020.1795601. [Epub ahead of print]
PMID: 32660355

 

Total Functional Score of Enhancer Elements Identifies Lineage-Specific Enhancers That Drive Differentiation of Pancreatic Cells.
Malladi VS, Nagari A, Franco HL, Kraus WL.
Bioinform Biol Insights. 2020 Jul 1;14:1177932220938063. doi: 10.1177/1177932220938063. eCollection 2020.
PMID: 32655276

 

Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals. 

Colicino E, Marioni R, Ward-Caviness C, Gondalia R, Guan W, Chen B, Tsai PC, Huan T, Xu G, Golareh A, Schwartz J, Vokonas P, Just A, Starr JM, McRae AF, Wray NR, Visscher PM, Bressler J, Zhang W, Tanaka T, Moore AZ, Pilling LC, Zhang G, Stewart JD, Li Y, Hou L, Castillo-Fernandez J, Spector T, Kiel DP, Murabito JM, Liu C, Mendelson M, Assimes T, Absher D, Tsaho PS, Lu AT, Ferrucci L, Wilson R, Waldenberger M, Prokisch H, Bandinelli S, Bell JT, Levy D, Deary IJ, Horvath S, Pankow J, Peters A, Whitsel EA, Baccarelli A.

Aging (Albany NY). 2020 Jul 22;12. doi: 10.18632/aging.103408. Online ahead of print.

PMID: 32697766

 

Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer. 

Liao C, Zhang Y, Fan C, Herring LE, Liu J, Locasale JW, Takada M, Zhou J, Zurlo G, Hu L, Simon JM, Ptacek TS, Andrianov VG, Loza E, Peng Y, Yang H, Perou CM, Zhang Q.

Cancer Discov. 2020 Jul 20:CD-20-0288. doi: 10.1158/2159-8290.CD-20-0288. Online ahead of print.

PMID: 32690540

 

Integration of clinical parameters, genotype and epistaxis severity score to guide treatment for hereditary hemorrhagic telangiectasia associated bleeding.
Beckman JD, Li Q, Hester ST, Leitner O, Smith KL, Kasthuri RS.
Orphanet J Rare Dis. 2020 Jul 13;15(1):185. doi: 10.1186/s13023-020-01453-1.
PMID: 32660636

 

Building a Quality Management System in a Core Facility: A Genomics Core Case Study.
Gregory CW.
J Biomol Tech. 2020 Jul;31(2):57-65. doi: 10.7171/jbt.20-3102-004.
PMID: 32655325

 

Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines.
Mei W, Jiang Z, Chen Y, Chen L, Sancar A, Jiang Y.
Brief Bioinform. 2020 Jul 16. pii: bbaa135. doi: 10.1093/bib/bbaa135. [Epub ahead of print]
PMID: 32672832

 

Terminus enables the discovery of data-driven, robust transcript groups from RNA-seq data.
Sarkar H, Srivastava A, Bravo HC, Love MI, Patro R.
Bioinformatics. 2020 Jul 1;36(Supplement_1):i102-i110. doi: 10.1093/bioinformatics/btaa448.
PMID: 32657377

 

Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic: CHEST Expert Panel Report.
Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA.
J Am Coll Radiol. 2020 Jul;17(7):845-854. doi: 10.1016/j.jacr.2020.04.024. Epub 2020 Apr 23.
PMID: 32485147

 

Antipsychotic Behavioral Phenotypes in the Mouse Collaborative Cross Recombinant Inbred Inter-Crosses (RIX). 

Giusti-Rodríguez P, Xenakis JG, Crowley JJ, Nonneman RJ, DeCristo DM, Ryan A, Quackenbush CR, Miller DR, Shaw GD, Zhabotynsky V, Sullivan PF, Pardo-Manuel de Villena F, Zou F.

G3 (Bethesda). 2020 Jul 21:g3.400975.2020. doi: 10.1534/g3.120.400975. Online ahead of print.

PMID: 32694196