Department of Genetics faculty, postdocs, students and collaborators published five papers during June 28 – July 11, 2020.

 

The SKI proto-oncogene restrains the resident CD103<sup>+</sup>CD8<sup>+</sup> T cell response in viral clearance.
Wu B, Zhang G, Guo Z, Wang G, Xu X, Li JL, Whitmire JK, Zheng J, Wan YY.
Cell Mol Immunol. 2020 Jul 1. doi: 10.1038/s41423-020-0495-7. [Epub ahead of print]
PMID: 3261215

 

Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases.
Lu L, Liu X, Huang WK, Giusti-Rodríguez P, Cui J, Zhang S, Xu W, Wen Z, Ma S, Rosen JD, Xu Z, Bartels CF, Kawaguchi R, Hu M, Scacheri PC, Rong Z, Li Y, Sullivan PF, Song H, Ming GL, Li Y, Jin F.
Mol Cell. 2020 Jun 20. pii: S1097-2765(20)30392-0. doi: 10.1016/j.molcel.2020.06.007. [Epub ahead of print]
PMID: 32592681

 

SMNN: batch effect correction for single-cell RNA-seq data via supervised mutual nearest neighbor detection.
Yang Y, Li G, Qian H, Wilhelmsen KC, Shen Y, Li Y.
Brief Bioinform. 2020 Jun 26. pii: bbaa097. doi: 10.1093/bib/bbaa097. [Epub ahead of print]
PMID: 32591778

 

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.
Bowman BM, Montgomery SA, Schrank TP, Simon JM, Ptacek TS, Tamir TY, Muvlaney KM, Weir SJ, Nguyen TT, Murphy RM, Makowski L, Hayes DN, Chen XL, Randell SH, Weissman BE, Major MB.
J Pathol. 2020 Jul 3. doi: 10.1002/path.5504. [Epub ahead of print]
PMID: 32619021

 

Human genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma.
Gorlov IP, Amos CI, Tsavachidis S, Begg C, Hernando E, Cheng C, Shen R, Orlow I, Luo L, Ernstoff MS, Parker J, Thomas NE, Gorlova OY, Berwick M.
Hum Mutat. 2020 Jul 9. doi: 10.1002/humu.24078. [Epub ahead of print]
PMID: 32643855