Department of Genetics Publications for September 24th – October 7th, 2023

Department of Genetics faculty, postdocs, students and collaborators published 12 papers during September 24th – October 7th, 2023.

 

Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors. 

Casasnovas-Nieves JJ, Rodríguez Y, Franco HL, Cadilla CL.

Genes (Basel). 2023 Aug 30;14(9):1733. doi: 10.3390/genes14091733.

PMID: 37761873 Free PMC article.

 

Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk. 

Tobias DK, Manning AK, Wessel J, Raghavan S, Westerman KE, Bick AG, Dicorpo D, Whitsel EA, Collins J, Correa A, Cupples LA, Dupuis J, Goodarzi MO, Guo X, Howard B, Lange LA, Liu S, Raffield LM, Reiner AP, Rich SS, Taylor KD, Tinker L, Wilson JG, Wu P, Carson AP, Vasan RS, Fornage M, Psaty BM, Kooperberg C, Rotter JI, Meigs J, Manson JE; TOPMed Diabetes Working Group; National Heart, Lung, and Blood Institute TOPMed Consortium.

Diabetes Care. 2023 Sep 27:dc230805. doi: 10.2337/dc23-0805. Online ahead of print.

PMID: 37756531

 

Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses. 

Wang M, Rousseau B, Qiu K, Huang G, Zhang Y, Su H, Le Bihan-Benjamin C, Khati I, Artz O, Foote MB, Cheng YY, Lee KH, Miao MZ, Sun Y, Bousquet PJ, Hilmi M, Dumas E, Hamy AS, Reyal F, Lin L, Armistead PM, Song W, Vargason A, Arthur JC, Liu Y, Guo J, Zhou X, Nguyen J, He Y, Ting JP, Anselmo AC, Huang L.

Nat Biotechnol. 2023 Sep 25. doi: 10.1038/s41587-023-01957-8. Online ahead of print.

PMID: 37749267

 

Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1. 

Sanz M, Weideman AMK, Ward AR, Clohosey ML, Garcia-Recio S, Selitsky SR, Mann BT, Iannone MA, Whitworth CP, Chitrakar A, Garrido C, Kirchherr J, Coffey AR, Tsai YH, Samir S, Xu Y, Copertino D, Bosque A, Jones BR, Parker JS, Hudgens MG, Goonetilleke N, Soriano-Sarabia N.

Front Immunol. 2023 Sep 6;14:1219250. doi: 10.3389/fimmu.2023.1219250. eCollection 2023.

PMID: 37744358 Free PMC article.

 

An efficient machine learning framework to identify important clinical features associated with pulmonary embolism. 

Zou B, Zou F, Cai J.

PLoS One. 2023 Sep 28;18(9):e0292185. doi: 10.1371/journal.pone.0292185. eCollection 2023.

PMID: 37768933 Free PMC article.

 

The Tbx20-TLE interaction is essential for the maintenance of the second heart field. 

Edwards W, Bussey OK, Conlon FL.

Development. 2023 Sep 27:dev.201677. doi: 10.1242/dev.201677. Online ahead of print.

PMID: 37756602

 

ATM/Chk2 and ATR/Chk1 Pathways Respond to DNA Damage Induced by Movento^® 240SC and Envidor^®240SC Keto-Enol Insecticides in the Germarium of Drosophila melanogaster. 

González-Marín B, Calderón-Segura ME, Sekelsky J.

Toxics. 2023 Sep 6;11(9):754. doi: 10.3390/toxics11090754.

PMID: 37755764 Free PMC article.

 

Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study. 

Wang Y, Selvaraj MS, Li X, Li Z, Holdcraft JA, Arnett DK, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Cade BE, Carlson JC, Carson AP, Chen YI, Curran JE, de Vries PS, Dutcher SK, Ellinor PT, Floyd JS, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, Guo X, He J, Heard-Costa N, Hildalgo B, Hou L, Irvin MR, Joehanes R, Kaplan RC, Kardia SL, Kelly TN, Kim R, Kooperberg C, Kral BG, Levy D, Li C, Liu C, Lloyd-Jone D, Loos RJ, Mahaney MC, Martin LW, Mathias RA, Minster RL, Mitchell BD, Montasser ME, Morrison AC, Murabito JM, Naseri T, O’Connell JR, Palmer ND, Preuss MH, Psaty BM, Raffield LM, Rao DC, Redline S, Reiner AP, Rich SS, Ruepena MS, Sheu WH, Smith JA, Smith A, Tiwari HK, Tsai MY, Viaud-Martinez KA, Wang Z, Yanek LR, Zhao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Rotter JI, Lin X, Natarajan P, Peloso GM.

Am J Hum Genet. 2023 Oct 5;110(10):1704-1717. doi: 10.1016/j.ajhg.2023.09.003.

PMID: 37802043

 

Swedish multimodal cohort of patients with anxiety or depression treated with internet-delivered psychotherapy (MULTI-PSYCH). 

Boberg J, Kaldo V, Mataix-Cols D, Crowley JJ, Roelstraete B, Halvorsen M, Forsell E, Isacsson NH, Sullivan PF, Svanborg C, Andersson EH, Lindefors N, Kravchenko O, Mattheisen M, Danielsdottir HB, Ivanova E, Boman M, Fernández de la Cruz L, Wallert J, Rück C.

BMJ Open. 2023 Oct 4;13(10):e069427. doi: 10.1136/bmjopen-2022-069427.

PMID: 37793927 Free PMC article.

 

Analysis of strain, sex, and diet-dependent modulation of gut microbiota reveals candidate keystone organisms driving microbial diversity in response to American and ketogenic diets. 

Salvador AC, Huda MN, Arends D, Elsaadi AM, Gacasan CA, Brockmann GA, Valdar W, Bennett BJ, Threadgill DW.

Microbiome. 2023 Oct 3;11(1):220. doi: 10.1186/s40168-023-01588-w.

PMID: 37784178 Free PMC article.

 

SETting up the genome: KMT2D and KDM6A genomic function in the Kabuki syndrome craniofacial developmental disorder. 

Shpargel KB, Quickstad GA.

Birth Defects Res. 2023 Oct 6. doi: 10.1002/bdr2.2253. Online ahead of print.

PMID: 37800171 Review.

 

Longitudinal development of the cerebellum in human infants during the first 800 days. 

Wang Y, Chen L, Wu Z, Li T, Sun Y, Cheng J, Zhu H, Lin W, Wang L, Huang W, Li G; UNC/UMN Baby Connectome Project Consortium.

Cell Rep. 2023 Apr 25;42(4):112281. doi: 10.1016/j.celrep.2023.112281. Epub 2023 Mar 23.

PMID: 36964904