Key words: systems biology, signal transduction, cell fate decisions, cell cycle
We study the behavior of individual cells and try to understand how groups of cells work together to carry out emergent functions. We are especially interested in “irreversible” cell fates such as apoptosis, senescence, and differentiation. How does a given cell convert molecular signals into a permanent decision? How do groups of cells balance these decisions? We use a variety of experimental and computational approaches to investigate these questions including molecular profiling, time-lapse microscopy, computational modeling, and machine learning. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these choices to treat disease.
- Faculty Mentoring Workshop for Biomedical Researchers
Training Program Affiliations:
- Bioinformatics and Computational Biology
- Genetics and Molecular Biology
We are accepting BBSP rotation students. If you are interested in doing a rotation in the lab, please send Jeremy an email and arrange a time to come by and discuss a potential rotation project.
We are interested in attracting candidates with a strong background in molecular biology, experience with human cell culture and affinity to theory and computation. Experience with fluorescence microscopy and genome editing is a plus. In addition we are looking for candidates with a background in math, physics, or other quantitative disciplines who are interested in applying theory to systems-level questions in biology. To apply, e-mail a cover letter, CV and a list of three references to Jeremy.
Jeremy Purvis in UNC Genetics News
February 8, 2021
Department of Genetics Publications for Jan. 24 – Feb. 6, 2021
Department of Genetics faculty, postdocs, students and collaborators published twenty papers during Jan. 24 – Feb. 6, 2021.
September 11, 2020
Jeremy Purvis, PhD Awarded R01 from NIGMS
Dr. Jeremy Purvis (Associate Professor, Genetics) was awarded an R01 grant from the National Institute of General Medical Sciences (NIGMS) for his proposal titled “Computational Models of the Human Cell Cycle to Reveal Disease Mechanism and Inform Treatment”.
July 27, 2020
Department of Genetics Publications for July 12-25, 2020
Department of Genetics faculty, postdocs, students and collaborators published twelve papers during July 12-25, 2020.
October 9, 2019
Department of Genetics Publications for September 22 – October 5, 2019
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during Sept. 22 – Oct. 5, 2019.
September 23, 2019
Department of Genetics Publications for September 8-21, 2019
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during Sept. 8-21, 2019.
July 1, 2019
Dr. Jeremy Purvis Promoted to Associate Professor
Jeremy Purvis, PhD has been promoted to the rank of Associate Professor with permanent tenure in the Department of Genetics, effective July 1, 2019.
June 24, 2019
Department of Genetics Publications for June 2-15, 2019
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during June 2-15, 2019.
May 6, 2019
Department of Genetics Publications from April 21-May 4, 2019
Department of Genetics faculty, postdocs, students and collaborators published fourteen papers during April 21-May 4, 2019.
March 27, 2019
Department of Genetics Publications for March 10-23, 2019
Department of Genetics faculty, postdocs, students and collaborators published fifteen papers during March 10-23, 2019.
November 30, 2018
Jeremy Purvis, PhD Receives CAREER Award from National Science Foundation
Jeremy Purvis, Assistant Professor, Department of Genetics was awarded a five-year grant through the Faculty Early Career Development Program of the National Science Foundation.