Research Interests
Key words: systems biology, signal transduction, cell fate decisions, cell cycle
We study the behavior of individual cells and try to understand how groups of cells work together to carry out emergent functions. We are especially interested in “irreversible” cell fates such as apoptosis, senescence, and differentiation. How does a given cell convert molecular signals into a permanent decision? How do groups of cells balance these decisions? We use a variety of experimental and computational approaches to investigate these questions including molecular profiling, time-lapse microscopy, computational modeling, and machine learning. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these choices to treat disease.
Mentor Training:
- Faculty Mentoring Workshop for Biomedical Researchers
- REI Racial Equity Workshop Phase 1
Training Program Affiliations:
- Bioinformatics and Computational Biology
- Biostatistics
- Genetics and Molecular Biology
Publications
Opportunities
Graduate Students
We are accepting BBSP rotation students. If you are interested in doing a rotation in the lab, please send Jeremy an email and arrange a time to come by and discuss a potential rotation project.
Postdoctoral Positions
We are interested in attracting candidates with a strong background in molecular biology, experience with human cell culture and affinity to theory and computation. Experience with fluorescence microscopy and genome editing is a plus. In addition we are looking for candidates with a background in math, physics, or other quantitative disciplines who are interested in applying theory to systems-level questions in biology. To apply, e-mail a cover letter, CV and a list of three references to Jeremy.
Jeremy Purvis in UNC Genetics News
October 10, 2022
Department of Genetics Publications for September 25th – October 8th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 10 papers during September 25th – October 8th, 2022.
September 12, 2022
Department of Genetics Publications for August 28th – September 10th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during August 28th – September 10th, 2022.
September 6, 2022
Jeremy Purvis, PhD, Receives Administrative Equipment Supplement from NIGMS
Dr. Jeremy Purvis (Associate Professor, Genetics) has been awarded an Administrative Equipment Supplement from the National Institute of General Medical Sciences (NIGMS) for his existing grant titled “Computational models of the human cell cycle to reveal disease mechanism and inform treatment”.
August 29, 2022
Jeremy Purvis, PhD, Awarded Boost funding from SOM Dean’s Office
Dr. Jeremy Purvis (Associate Professor, Department of Genetics) was awarded Boost funding from the UNC School of Medicine (SOM) Dean’s Office for his project “Modeling and Targeting the Cell Cycle for Breast Cancer”.
February 28, 2022
Department of Genetics Publications February 13th – 26th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during February 13th – 26th 2022.
January 31, 2022
Department of Genetics Publications January 16th – 29th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 17 papers during January 16th – 29th, 2022.
December 12, 2021
Department of Genetics Publications November 28th – December 11th, 2021
Department of Genetics faculty, postdocs, students and collaborators published 13 papers during November 28th – December 11th, 2021.
November 29, 2021
Department of Genetics Publications November 14th – 27th 2021
Department of Genetics faculty, postdocs, students and collaborators published 16 papers during November 14th – 27th 2021.
February 8, 2021
Department of Genetics Publications for Jan. 24 – Feb. 6, 2021
Department of Genetics faculty, postdocs, students and collaborators published twenty papers during Jan. 24 – Feb. 6, 2021.
September 11, 2020
Jeremy Purvis, PhD Awarded R01 from NIGMS
Dr. Jeremy Purvis (Associate Professor, Genetics) was awarded an R01 grant from the National Institute of General Medical Sciences (NIGMS) for his proposal titled “Computational Models of the Human Cell Cycle to Reveal Disease Mechanism and Inform Treatment”.
