Research Interests
Keywords: Bioinformatics, Metagenomics, Microbial genomics, Genomic epidemiology
Dr. Jeremy Wang, Ph.D. is an Assistant Professor in the Genetics Department. With support from NIH/NIDDK and the UNC Center for Gastrointestinal Biology of Disease (CGIBD), Dr. Wang’s research focuses on the role of the adherent gut microbiome in inflammatory bowel diseases. He has developed and applied novel metagenomic sequencing technologies to characterize the taxonomic and functional composition of mucosally-associated microbial communities in mouse models of colitis. Using a combination of technologies including adaptive nanopore sequencing to deplete host DNA from tissue-associated samples, and full-length rRNA amplicon sequencing, Dr. Wang’s lab has demonstrated dramatically improved taxonomic specificity and greater sampling depth of complex host-associated metagenomic communities than is possible with commonly used approaches. Ongoing areas of research in the Wang lab include mapping temporal and spatial dynamics of colonization of the mucosal barrier by adherent-invasive E. coli; genomic epidemiology of bacterial and viral intestinal pathogens; and exploring the contribution of mucosa-associated microbiome to Crohn’s disease using host-depleted metagenomic sequencing.
Mentor Training:
- Bias 101
Publications
Jeremy Wang in UNC Genetics News
September 26, 2022
Jeremy Wang, PhD Awarded Genetics Faculty Research Support “Pivot” Grant
Dr. Jeremy Wang (Assistant Professor) was awarded a Faculty Research Support “Pivot” Grant from the Department of Genetics for his project focused on demonstrating efficient whole-genome Nanopore sequencing and assembly of Monkeypox virus (MPXV) genomes from clinical samples testing positive at UNC Medical Center’s Clinical Molecular Microbiology Lab (directed by Dr. Melissa Miller).
June 19, 2022
Department of Genetics Publications for June 5th – 18th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 16 papers during June 5th – 18th, 2022.
April 25, 2022
Department of Genetics Publications April 10th – 23rd, 2022
Department of Genetics faculty, postdocs, students and collaborators published 18 papers during April 10th – 23rd, 2022.
January 17, 2022
Department of Genetics Publications January 2nd – 15th 2022
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during January 2nd – 15th, 2022.
November 29, 2021
Department of Genetics Publications November 14th – 27th 2021
Department of Genetics faculty, postdocs, students and collaborators published 16 papers during November 14th – 27th 2021.
November 1, 2021
Department of Genetics Publications October 17th – 30th, 2021
Department of Genetics faculty, postdocs, students and collaborators published 14 papers during October 17th – 30th 2021.
September 9, 2021
The Power of Partnership
A collaboration among Carolina clinicians and researchers is leading the way in how we think about tracking viral variants.
September 7, 2021
Department of Genetics Publications August 22nd – September 4th 2021
Department of Genetics faculty, postdocs, students and collaborators published 9 papers during August 22nd – September 4th 2021. SnapHiC: a computational pipeline to identify chromatin loops from single-cell Hi-C data. Yu M, Abnousi A, Zhang Y, Li G, Lee L, Chen Z, Fang R, Lagler TM, Yang Y, Wen J, Sun Q, Li Y, …
August 25, 2021
Keriayn Smith, PhD and Jeremy Wang, PhD Receive COVID-19 Supplemental Funding from UNC School of Medicine Office of Research
Drs. Keriayn Smith (Assistant Professor, Genetics) and Jeremy Wang (Assistant Professor, Genetics) were each awarded $10K grants from the UNC SOM Office of Research as part of the COVID-19 Supplemental Funding program.
July 24, 2021
Department of Genetics Publications for July 11th – July 24th, 2021
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during July 11th - July 24th, 2021.