Research Interests
Keywords: prostate cancer, therapy resistance, transcriptional regulation, epigenetics, targeted therapy, androgen receptor and its variants and cofactors
Dr. Cai received her PhD from University of California, San Diego (UCSD) and conducted postdoctoral trainings at Memorial Sloan Kettering Cancer Center (MSKCC) and UNC-Chapel Hill Lineberger Comprehensive Cancer Center (LCCC).
The objective of her research group is to decipher genetic and epigenetic mechanisms underlying the progression of castration-resistant prostate cancer (CRPC), a lethal disease, and to develop novel treatment strategies. Dr. Cai routinely takes the integrated biochemical, genomic and cancer biology approaches and cutting-edge technologies to study the roles of various transcription factors and chromatin regulators during the development of CRPC. Completion of the research aims should provide important insights into how CRPC develops and how we may treat CRPC more effectively.
Mentor Training:
Publications
Ling Cai in UNC Genetics News
February 28, 2022
Department of Genetics Publications February 13th – 26th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during February 13th – 26th 2022.
January 3, 2022
Department of Genetics Publications December 12th, 2021 – January 1st, 2022
Department of Genetics faculty, postdocs, students and collaborators published 14 papers during December 12th, 2021 – January 1st, 2022.
April 19, 2021
Department of Genetics Publications for April 4-17, 2021
Department of Genetics faculty, postdocs, students and collaborators published fifteen papers during April 4-17, 2021. Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors. Ahmed SK, Haese NN, Cowan JT, Pathak V, Moukha-Chafiq O, Smith VJ, Rodzinak KJ, Ahmad F, Zhang S, Bonin KM, Streblow AD, Streblow CE, Kreklywich CN, Morrison C, Sarkar S, Moorman N, …
March 8, 2021
Department of Genetics Publications for February 21 – March 6, 2021
Department of Genetics faculty, postdocs, students and collaborators published twelve papers during February 21 – March 6, 2021.
November 16, 2020
Department of Genetics Publications for November 1-14, 2020
Department of Genetics faculty, postdocs, students and collaborators published nine papers during November 1-14, 2020.
February 10, 2020
Department of Genetics Publications for Jan. 26 – Feb. 8, 2020
Department of Genetics faculty, postdocs, students and collaborators published fifteen papers during Jan. 26 – Feb. 8, 2020.
December 17, 2019
Department of Genetics Publications for Dec. 1-14, 2019
Department of Genetics faculty, postdocs, students and collaborators published nine papers during Dec. 1-14, 2019.
September 23, 2019
Department of Genetics Publications for September 8-21, 2019
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during Sept. 8-21, 2019.
