Department of Genetics Publications for February 21 – March 6, 2021

Department of Genetics faculty, postdocs, students and collaborators published twelve papers during February 21 – March 6, 2021.

 

 

Highly dampened blood transcriptome response in HIV patients after influenza infection. 

Sellers SA, Fischer WA 2nd, Heise MT, Schughart K.

Sci Rep. 2021 Feb 24;11(1):4465. doi: 10.1038/s41598-021-83876-9.

PMID: 33627703

 

Protein-based immune profiles of basal-like vs. luminal breast cancers. 

Walens A, Olsson LT, Gao X, Hamilton AM, Kirk EL, Cohen SM, Midkiff BR, Xia Y, Sherman ME, Nikolaishvili-Feinberg N, Serody JS, Hoadley KA, Troester MA, Calhoun BC.

Lab Invest. 2021 Feb 23. doi: 10.1038/s41374-020-00506-0. Online ahead of print.

PMID: 33623115

 

Behavioral characterization of a novel Cisd2 mutant mouse. 

Gaines CH, Snyder AE, Ervin RB, Farrington J, Walsh K, Schoenrock SA, Tarantino LM.

Behav Brain Res. 2021 Feb 18:113187. doi: 10.1016/j.bbr.2021.113187. Online ahead of print.

PMID: 33610659

 

CRISPR-based knockin mutagenesis of the pioneer transcription factor FOXA1: optimization of strategies for multi-allelic proteins in cancer cells. 

Li S, Garay JP, Tubbs CA, Franco HL.

FEBS Open Bio. 2021 Mar 5. doi: 10.1002/2211-5463.13139. Online ahead of print.

PMID: 33666335

 

Germ granule dysfunction is a hallmark and mirror of Piwi mutant sterility. 

Spichal M, Heestand B, Billmyre KK, Frenk S, Mello CC, Ahmed S.

Nat Commun. 2021 Mar 3;12(1):1420. doi: 10.1038/s41467-021-21635-0.

PMID: 3365851

 

Genetic Background Shapes Phenotypic Response to Diet for Adiposity in the Collaborative Cross. 

Yam P, Albright J, VerHague M, Gertz ER, Pardo-Manuel de Villena F, Bennett BJ.

Front Genet. 2021 Feb 11;11:615012. doi: 10.3389/fgene.2020.615012. eCollection 2020.

PMID: 33643372

 

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors. 

Jefferys SR, Burgos SD, Peterson JJ, Selitsky SR, Turner AM, James LI, Tsai YH, Coffey AR, Margolis DM, Parker J, Browne EP.

PLoS Pathog. 2021 Feb 26;17(2):e1009346. doi: 10.1371/journal.ppat.1009346. Online ahead of print.

PMID: 33635929

 

CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition. 

Musicant AM, Parag-Sharma K, Gong W, Sengupta M, Chatterjee A, Henry EC, Tsai YH, Hayward MC, Sheth S, Betancourt R, Hackman TG, Padilla RJ, Parker JS, Giudice J, Flaveny CA, Hayes DN, Amelio AL.

Cell Rep. 2021 Feb 23;34(8):108768. doi: 10.1016/j.celrep.2021.108768.

PMID: 33626346

 

Genetic architecture of Tourette syndrome: our current understanding. 

Domènech L, Cappi C, Halvorsen M.

Psychol Med. 2021 Feb 22:1-9. doi: 10.1017/S0033291721000234. Online ahead of print.

PMID: 33612126

 

ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. 

Li J, Galbo PM Jr, Gong W, Storey AJ, Tsai YH, Yu X, Ahn JH, Guo Y, Mackintosh SG, Edmondson RD, Byrum SD, Farrar JE, He S, Cai L, Jin J, Tackett AJ, Zheng D, Wang GG.

Nat Commun. 2021 Feb 16;12(1):1045. doi: 10.1038/s41467-021-21357-3.

PMID: 33594072

 

Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury. 

Niehaus JK, Taylor-Blake B, Loo L, Simon JM, Zylka MJ.

Neuron. 2021 Feb 24:S0896-6273(21)00118-5. doi: 10.1016/j.neuron.2021.02.018. Online ahead of print.

PMID: 33667343

 

On kernel machine learning for propensity score estimation under complex confounding structures. 

Zou B, Mi X, Tighe PJ, Koch GG, Zou F.

Pharm Stat. 2021 Feb 22. doi: 10.1002/pst.2105. Online ahead of print.

PMID: 33619894