OoR Funding

Funds Adminstered by the OoR


The School of Medicine's new Strategic Plan includes a new annual award cycle - the Translational Team Science (TTS) Award- administered in partnership with NC TraCS.  This award is aimed at capitalizing on the "culture of collaboration" at UNC Chapel Hill to foster new synergistic interdisciplinary teams of basic science and clinical investigators.  The award is not restricted to human subjects and tissues, and proposals may include research using cellular and animal model systems; however the project should translate across basic and clinical disciplines.

There are multiple stages of TTS applications and awards (see application process, below).  After submission of an initial one page Concept paper, selected teams will be invited to submit a full Feasibility proposal for review.  If awarded, TTS Phase I Feasibility grants will provide a 12-month period to begin to fully engage team members in the development of a competitive continuation proposal for TTS Phase II (2 years). Advancement to the next award stage is contingent on the merit of the proposed plan and progress in the prior period. The expectation is that these awards will provide the planning time and initial funds to support early stage denovo research teams that would otherwise not be possible.  This would ultimately lead to submission of novel interdisciplinary program project grants and multiple PI R01s by UNC SOM investigators.

TTSA awards will be made jointly with NC TraCS pilot funding. For teams led by  SOM PIs, the SOM will provide the funding match for TraCS funds.  For other teams led by non-SOM PIs, matched funds should be provided by other appropriate units.  Review of phase I and phase II applications (defined below) will be done by the NC TraCS review panel with equal consideration for early to late stage translational studies.

The inaugural TTSA RFA was issued in October 2013.    A summary of the teams and projects awarded are listed here.

Solicitations for new concepts are released in the fall. . Please see the TTSA RFP for a description of the program and guidelines for submission.


The SOM Office of Research has started a new award mechanism for pilot funding - Emerging Challenges in Biomedical Research (ECBR).  The intent of the award is to provide support for innovative, early stage research relevant to NIH priorities.  The supported research is expected to lead to submission of novel interdisciplinary program project grants and multiple PI R01s by UNC SOM investigators.  Preference will be given to new projects and ideas from individual investigators and cross-cutting teams with the highest impact research across the spectrum of basic and clinical research.  The funds are not meant as a supplement of bridge to an existing project. 

The purpose of the Winter 2017 challenge is to capture the broad interdisciplinary expertise of SOM faculty relevant to Alzheimer’s disease research.  The rise in Alzheimer’s disease underscores a need for timely research and increased funding by NIH and the 21st Century Cures Act. The NIH’s investment in Alzheimer’s research for 2017 is summarized here: https://www.nia.nih.gov/alzheimers/bypass-budget-fy2017.   The Winter 2017 RFP details can be found here.

It is anticipated that future funding challenges will be aligned with high profile research objectives such as concept clearances from NIH institutes and the Common Fund.  Click here for information on the previous award recipients and their projects.

Collaborative Cross Pilot Program

The Collaborative Cross (CC) is a unique UNC resource consisting of a mouse multiparent population derived from eight inbred strains.  High level and uniform distribution of genetic variants genome-wide and the presence of combinations of alleles derived from three different subspecies, found only in this population, make this resource uniquely suited to test and characterize the role of genetic diversity in the etiology of biomedical traits.  This resource is maintained and distributed by the Systems Genetics Core Facility at UNC.

Successful pilot projects will have access to 96 CC mice at $10.00 per mouse.  The CC strains allocated to each pilot project will be based on availability and researchers cannot select specific strains. 

An external review committee will review the proposals on a quarterly basis.Submissions will be accepted quarterly on the following deadlines:  February 1, May 1, August 1, November 1

The RFP can be found here.  Please contact Jennifer Brennan in the Office of Research with any questions.  Proposals can be emailed directly to Jennifer at jenbren@med.unc.edu.  


    A short description of the internal research funding opportunities available to faculty and their deadlines can be found here.


    The OoR can assist departments and centers with startup and retention packages, but never funds the full package.  Chairs and Center Directors should make requests for these funds as early in the process as possible.  OoR contribution: 25% of the package, up to $100,000.  The OoR's contribution will be disbursed to the department over 2 or 3 years.  If you need to request startup or retention funds, contact the Office of Research.


    Bridge funding applications are accepted 3 times during the academic year: September, January and April.  A memo is sent to Chairs and Center Directors to share with their faculty giving specific due dates.  Generally the memo is sent out about 3 weeks before the due date.  The current memo can be found here.  Eligibility criteria:

    • The grant has been reviewed and received a written critique
    • The PI has no more than 2 active R01s or the equivalent level of funding
    • The PI does not have additional sources of lab support, e.g. trust fund
    • If the grant's NIH number identifies the grant as a 'new' grant, the PI must include a cover letter explaining how the new grant is a repackaged version of previously funded research
    • The grant under consideration must be administered in an SOM unit
    • The department/center agrees to match the funding from the Dean's Office.

    The application for bridge funding much include:

    • current 3-4 page NIH biosketch
    • research section of the original grant application
    • the NIH review of that application
    • a draft rebuttal for the revised application
    • proposed budget for the bridge funds.

    Applications for or questions about bridge funding should be emailed to



    The Core Facilities Advocacy Committee [CFAC] is responsible for disbursing emergency and equipment funds for Core Facilities.  Emergency funds can be used for assistance with salaries and service contracts, purchase of small equipment needs [~$5-25K] and methodology development.  Equipment funds can be used for the purchase of instruments ranging from $30-100K and for cost-share amounts in conjunction with instrumentation grants.  The CFAC generally issues requests for funding applicaitons (RFAs) twice a year.  Emergency requests are  considered throughout the year as funds allow. 
    Please contact for more information