“Ras History: The Saga Continues.” Small GTPases 1(1):2-27.
This is the first volume, first issue, first article, and first cover of Small GTPases journal. About the cover [http://www.landesbioscience.com/journals/smallgtpases]
“Engineered allosteric activation of kinases in living cells.” Nature Biotechnology June 27, 2010 [epub before publication].
An article in UNC School of Medicine news [https://www.med.unc.edu/www/news/2010/june/technique-enables-precise-control-of-protein-activity-in-living-cells/?searchterm=technique-enables-precise-control-of-protein-activity-in-living-cells]
“Systematic Analysis of Essential Genes Reveals Important Regulators of G Protein Signaling.” Molecular Cell 38(5): 746-757, 2010.
Highlighted in Science Signaling Editor’s Choice June 29, 2010 as “G Protein Signaling Is Not a Done Deal.” [http://stke.sciencemag.org/cgi/content/abstract/sigtrans;3/128/ec191]
“Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype.” J Biol Chem 285:11760-11764.
“Hippocampal Short- and Long-term Plasticity are not Modulated by Astrocyte Ca2+ Signaling.” Science 327(5970): 1250-1254, 2010.
Commentary in Science on paper [http://www.sciencemag.org/cgi/content/summary/327/5970/1212]
Nature’s Highlighting of paper [http://www.nature.com/nature/journal/v464/n7286/pdf/464144d.pdf]
Nature Review Neuroscience’s Highlighting of paper [http://www.nature.com/nrn/journal/v11/n5/full/nrn2847.html]
A link for free access to Science’s online full-text article can be found on the McCarthy faculty page under publications. [https://www.med.unc.edu/pharm/people/primaryfaculty/ken-d-mccarthy-1/ken-d-mccarthy]
Related article: “The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis.” Mol Cell Biol 29(4): 1035-1049.
Online cover image and description [http://mcb.asm.org/content/vol30/issue3/cover.dtl]
“Predicting new molecular targets for known drugs.” Nature 462(7270):175-81, 2009.
“The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis.” Cell 138:990-1004.
“Genetically-encoded photoactivatable Rac reveals spatiotemporal coordination of Rac and Rho during cell motility.” Nature 461: 104-110, 2009. View movie of cell ruffles induced in a HeLa cell expressing PA-Rac1. See more supplemental movies. [http://www.nature.com/nature/journal/v461/n7260/suppinfo/nature08241.html]
“Coordination of Rho GTPase activities during cell protrusion.” Nature, 461: 99-103, 2009/
