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Dr. Nicholas G. Brown of UNC-CH presents
September 26, 2023 @ 4:00 pm - 5:00 pm
Nicholas G. Brown, PhD
Assistant Professor
Department of Pharmacology
University of North Carolina at Chapel Hill
Title of talk: “Mechanisms of polyubiquitination by the Anaphase-Promoting Complex/Cyclosome”
This seminar will be in 1131 Bioinformatics.
Please join us and show support for our seminar speakers!
(For those unable to attend, a zoom link is available upon request to MiMi Le.)
Host: Henrik Dohlman
About Dr. Brown’s research:
The overarching goal of my research program is to understand the system of inter- and intra-molecular interactions that dynamically regulate the catalytic mechanisms of enzymes to precisely time the events of the cell cycle. We employ a hybrid technological approach, including enzyme kinetics, mutagenesis, X-ray crystallography, NMR spectroscopy, and cryo-EM, to characterize these molecular machines. Our results provide mechanistic insight into the cell cycle that will influence the drug design of cancer therapeutics. ~ from The Nicholas G. Brown lab website
