Welcome to the Pharmacology Department!

Henrik Dolman, PhD, ChairOur Graduate Program is dedicated to the training of outstanding scientists in the pharmacological sciences. 
An outstanding graduate program is a high priority of our department, and the training faculty participate fully at all levels. Our department ranks consistently in the highest levels of NIH funding for pharmacology departments nationwide and a great diversity of research areas is available to trainees. more

The Department of Pharmacology ranks #3 in the nation in NIH research funding in its field.

Our Global Science Ranking: #2 In the World in Pharmacology and Toxicology Research and Publications, according to U.S. News & World Report's Best Global Universities 2018 report.

Carolina ranked top college value for 16th time in American public higher education, according to Kiplinger’s Personal Finance! 

Roth Lab Scientists Take a Big Step toward Building a Better Opioid

Kappa Opioid Receptor in the Active StateFor the first time, scientists at the University of North Carolina School of Medicine and collaborators solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. The lead researchers, Pharmacology Distinguished Professor, Bryan Roth, MD, PhD, and postdocs Tao Che, PhD and Daniel Wacker, PhD, then created a new drug-like compound that activates only that receptor, a key step in the development of better pain medications.

The research, published in the journal Cell, shows a route toward creating opioids that relieve pain without causing the severe side effects at the heart of the opioid epidemic. read more...

WRAL News Highlights Roth Lab's New Drug-Like Compound That Could Treat Pain Without Addiction

WRAL News Highlights Roth Lab Opioid ResearchWRAL News highlights Bryan Roth's development of a new drug-like compound that targets a kappa opioid receptor in the brain that can relieve pain without the negative side effect of addiction. This discovery creates a pathway for the development of better pain medicines.

Watch the WRAL News video here...
Read more on Wral Tech Wire...

Nicholas Lab Shows How Gonorrhea became a Drug-Resistant Superbug

Photo of Robert A. Nicholas 130x150Rob Nicholas and lab members Samuel Kerr, Yang Tan and Joshua Tomberg, and collaborators show how the gonorrhea bacterium resists last-resort antibiotic ceftriaxone while maintaining a robust growth rate. “The first step in stopping a drug-resistant bacterium is figuring out how it becomes resistant to antibiotics that once were able to kill it....Our results give us clues to how ceftriaxone-resistant gonorrhea is emerging, why this is such a looming problem, and what to focus on to limit it.” read more...

Song Lab Publishes Cover Paper in Cell Stem Cell

On the cover: In this issue, Bao et al. (604–617) show that long-range GABAergic projections from medial septum (MS) are necessary and sufficient for regulating neurogenesis through dentate local PV interneurons. The cover image is an artistic modification of the MS GABAergic projections acquired from Micro-Optical Sectioning Tomography (MOST) by Dr. Hui Gong from HUST. Flying birds allude to messengers sending GABA transmitter to the neurogenic niche. The lake and forest pictured below represent local PV interneurons nourishing neural stem cells. Cover designed by Hechen Bao and Mengting Dai.Congratulations to the Song lab for publishing the cover paper for the November 2, 2017 issue of Cell Stem Cell! The paper is titled, "Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis"!  The researchers identified a neurogenesis-controlling brain circuit that runs from near the front of the brain back to the hippocampus, a learning- and memory-related structure. The hippocampus is one of the major sites of neurogenesis in the adult human brain, and the circuit that Song’s team has identified regulates this neuron-producing process. read more...

Our 2018 Carolina Summer Fellowship Students Arrive!

2018 CSF students back row (L to R): Dylan Shuler, Nika Fendler, Garima Tomar and Sheloren Deering; front row (L to R): Larshe Moore, Sara Hudson, Daphne Gambrell-Sanders, Karson Guthrie and Alex Tribo.

We welcome our nine new Carolina Summer Fellowship Program students!
learn more...

Justin Watkins Selected as 3-yr SPIRE Fellow

Postdoc in Alan Jones' lab and recipient of SPIRE 3-yr FellowshipCongratulations to Dr. Justin Watkins, PhD, a postdoc in Alan Jones Lab, who has been selected as a 3-yr SPIRE Fellow (Seeding Postdoctoral Innovators in Research & Education). His Fellowship will begin Sept 1st, 2018.  read more...

Visit Us On Facebook!

Facebook logo
The Pharmacology Department has launched our Facebook Page. Please visit and like us on Facebook!