Community Engagement Committee, Community Engagement
Director of cryo-EM Core, Associate Professor
Research: Cellular and Structural biology, Biological Electron Microscopy, Cryo-electron microscopy
CB# 5536, Glaxo Rm 008
919-962-5536 | Email
Cryo-EM Core Overview
The UNC CryoEM Core was established in 2019 to provide researchers with access to cutting-edge imaging, technical support, and training in cryoEM. Since then, it has grown significantly, developing new cryoEM technologies and serving a large user base across diverse fields in the life sciences. The core’s comprehensive services begin with project planning and extend through high-resolution data collection and processing for key modalities like single-particle cryoEM, cryo-electron tomography, and cryoTEM of nanoparticles.
The core’s successful pipeline has been used to determine over 100 high-resolution structures of various macromolecular complexes, including soluble and membrane proteins. The core also offers advanced methods for sample preparation that aid in the recovery of low-abundant and fragile macromolecular assemblies. The core maintains a strong commitment to education, providing workshops and structured training with required assessments for independent use of the CryoTEM and Vitrobot. Furthermore, the facility is active in method development to provide customers with access to new research tools. Continue reading about this Core.
