June 8, 2020
SOM / NCTraCS ECBR pilot grant application titled “Measurement of plasma biomarkers to determine the mechanism of the coagulopathy in COVID-19 patients” Funding in the amount of $50,000 will be provided jointly by the School of Medicine and NCTraCS and is for a 12-month period.
May 27, 2020
Clinical knowledge about COVID-19-associated coagulopathy, including risk factors for development and how to prevent and manage hypercoagulability and thrombosis, continue to evolve as new data emerge from studies worldwide. Link to article
May 8, 2020
Congratulations to Dr. Nigel Mackman for the September 2019 ATVB Cover Award! Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) An award for the best cover of the previous year will be given at the ATVB Annual Conference held in the Spring. The covers are available at both Facebook and Twitter (@atvbahajournals) as well as below. Link …
May 8, 2020
The Kenneth M. Brinkhous Early Career Investigator Prize in Thrombosis recognizes outstanding endeavors by new investigators in fundamental and applied research in Thrombosis including the mechanism, detection, treatment, and prevention of thrombotic disorders. Evaluating the Impact of Thrombocytopenia and Platelet Transfusion on Bleeding and Thrombosis in the Setting of Anti-Platelet Therapy Robert H Lee | …
May 7, 2020
Treatment with Blood Thinners Improves Survival in Sickest Covid-19 Patients – Dr. Stephan Moll (Physician’s Weekly)
May 7, 2020
Congratulations to Dr. Nigel Key, Director, UNC Blood Research Center, his work published in Haemophilia was among the top 10% downloaded papers in the 12 months following online publication Link to article: How to discuss gene therapy for haemophilia? A patient and physician perspective
April 27, 2020
Jane Little, MD, professor of medicine in the division of hematology and member of the UNC Blood Research Center, has received an Innovation Pilot Award from the UNC Center for Health Innovation for “OneSCD UNC: Improving Care for People with Sickle Cell Disease in North Carolina.” William Scheidler, MD, assistant professor in the department of …
April 20, 2020
UNC Blood Research Center member Dougald Monroe along with Keith Neeves of the University of Colorado in Denver are investigators on a newly funded NIH NHLBI grant. The grant, R01HL151984, which was awarded four years of funding is titled An integrated computational and experimental approach to understanding the hemostatic response during treatment of bleeding. These …
March 27, 2020
Nigel Key, MD, the Harold R. Roberts Distinguished Professor of Medicine and Pathology and director of the UNC Blood Research Center published a study that identifies the intrinsic coagulation pathway as a potential target to prevent thrombotic and inflammatory complications after RBC transfusion. The article “Red blood cell microvesicles activate the contact system, leading to …
March 27, 2020
Nigel S. Key, MB, ChB, FRCP Nigel Key, MB ChP FRCP, the Harold R. Roberts Distinguished Professor of Medicine and Pathology and director of the UNC Blood Research Center (BRC) has published important findings on the mechanism of thrombin generation induced by stored red blood cells (sRBC). In a recent study, first author Denis Noubouossie, …
March 26, 2020
High fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice Abstract: Obesity is a prevalent prothrombotic risk factor marked by enhanced fibrin formation and suppressed fibrinolysis. Fibrin both promotes thrombotic events and drives obesity pathophysiology, but a lack of essential analytical tools has left fibrinolytic mechanisms affected by obesity poorly defined. Using a …
December 13, 2019
My primary clinical and research interest focus is on sickle cell disease. Past efforts have focused on improving the care of patients with sickle cell disease through quality improvement initiatives such as improving time to antibiotics in children with SCD presenting with fevers as well as improving delivery of analgesia in the ED setting. As a Hispanic female physician, it is an honor and, indeed part of my mission as an academic physician, to serve as a mentor and sponsor to trainees, particularly those from backgrounds historically marginalized, underserved and underrepresented in medicine.