Latest Posts

Congratulations to Jean Marie Mwiza, a graduate research assistant in Dr. Bergmeier’s Lab, for recently receiving a prestigious predoctoral fellowship from AHA.  Jean Marie’s fellowship provides stipend support for 2 years for his project, titled “Determining the Platelet Signaling Pathway(s) Critical in Venous Thrombosis Pathogenesis”.

Nigel Key, MD, the Harold R. Roberts Distinguished Professor of Medicine and Pathology and director of the UNC Blood Research Center published a study that identifies the intrinsic coagulation pathway as a potential target to prevent thrombotic and inflammatory complications after RBC transfusion. The article “Red blood cell microvesicles activate...

Nigel S. Key, MB, ChB, FRCP Nigel Key, MB ChP FRCP, the Harold R. Roberts Distinguished Professor of Medicine and Pathology and director of the UNC Blood Research Center (BRC) has published important findings on the mechanism of thrombin generation induced by stored red blood cells (sRBC). In a recent...

High fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice Abstract: Obesity is a prevalent prothrombotic risk factor marked by enhanced fibrin formation and suppressed fibrinolysis. Fibrin both promotes thrombotic events and drives obesity pathophysiology, but a lack of essential analytical tools has left fibrinolytic mechanisms affected by...

Congratulations to Wolfgang Bergmeier, Ph.D., Associate Professor, Department of Biochemistry and Biophysics, in collaboration with a multi-institutional team, for publishing article in the journal Science Advances. Dr. Bergmeier and the team explain why platelet responses are associated with organ injury and mortality after cardiac surgeries and how platelets cause local...

My current research focuses on interventions to improve the transition process for patients with rare blood disorders, such as sickle cell disease, as they move from a pediatric centered care environment to adult health care facilities.

Being part of the BRC at UNC provides us with a unique opportunity to interact on a daily basis with world leaders in related areas of blood research. We are particularly excited about the fact that centers like the BRC bring together basic science with clinical expertise, thus providing a...

I am a clinician and clinical researcher focused on hemostasis. Many patients we evaluate for abnormal bleeding have a normal laboratory work-up despite clinically significant symptoms. The majority of these patients are women with histories of heavy menses, post-operative bleeding, and post-partum bleeding. I collaborate with BRC members to improve...

I am a clinical hematologist with an academic focus and national leadership role in the field of vascular anomalies. I built and co-directed the Vascular Anomalies Program at Vanderbilt University Medical Center and served as Associate Clinical Director of the Comprehensive Vascular Anomalies Program and Co-Director of the Pediatric Hereditary...

My primary clinical and research interest focus is on sickle cell disease. Past efforts have focused on improving the care of patients with sickle cell disease through quality improvement initiatives such as improving time to antibiotics in children with SCD presenting with fevers as well as improving delivery of analgesia...

My long-term research goals are to understand mechanisms involved in coagulation and develop novel therapies that augment the body’s native clotting and subsequent healing processes. A primary research focus in my group is the development of platelet-mimetic materials that participate in the natural coagulation cascade to promote hemostasis and enhance...

Dr. Marcus Carden is a Med/Peds hematologist who is part of the hematology faculty in the Departments of Pediatrics and Medicine at the UNC School of Medicine as an Assistant Professor and as the Director of the Pediatric Sickle Cell program. As a clinician for both pediatric and adult patients...