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Department of Genetics faculty, postdocs, students and collaborators published nine papers during April 19 – May 2, 2020.

 

Sequence variant analysis reveals poor correlations in microbial taxonomic abundance between humans and mice after gnotobiotic transfer.
Fouladi F, Glenny EM, Bulik-Sullivan EC, Tsilimigras MCB, Sioda M, Thomas SA, Wang Y, Djukic Z, Tang Q, Tarantino LM, Bulik CM, Fodor AA, Carroll IM.
ISME J. 2020 Apr 20. doi: 10.1038/s41396-020-0645-z. [Epub ahead of print]
PMID: 32313261

 

Rab27a plays a dual role in metastatic propensity of pancreatic cancer.
Kren N, Michaud D, Bagchi S, Greene K, Pylayeva-Gupta Y.
Sci Rep. 2020 Apr 30;10(1):7390. doi: 10.1038/s41598-020-64248-1.
PMID: 32355248

 

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross.
Noll KE, Whitmore AC, West A, McCarthy MK, Morrison CR, Plante KS, Hampton BK, Kollmus H, Pilzner C, Leist SR, Gralinski LE, Menachery VD, Schäfer A, Miller D, Shaw G, Mooney M, McWeeney S, Pardo-Manuel de Villena F, Schughart K, Morrison TE, Baric RS, Ferris MT, Heise MT.
Cell Rep. 2020 Apr 28;31(4):107587. doi: 10.1016/j.celrep.2020.107587.
PMID: 32348764

 

SMART-Q:  An Integrative Pipeline Quantifying Cell Type-Specific RNA Transcription.
Yang X, Bergenholtz S, Maliskova L, Pebworth MP, Kriegstein AR, Li Y, Shen Y.
PLoS One. 2020 Apr 29;15(4):e0228760. doi: 10.1371/journal.pone.0228760. eCollection 2020.
PMID: 32348304

 

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease.
Bryois J, Skene NG, Hansen TF, Kogelman LJA, Watson HJ, Liu Z; Eating Disorders Working Group of the Psychiatric Genomics Consortium; International Headache Genetics Consortium; 23andMe Research Team, Brueggeman L, Breen G, Bulik CM, Arenas E, Hjerling-Leffler J, Sullivan PF.
Nat Genet. 2020 Apr 27. doi: 10.1038/s41588-020-0610-9. [Epub ahead of print]
PMID: 32341526

 

Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration.
Fragola G, Mabb AM, Taylor-Blake B, Niehaus JK, Chronister WD, Mao H, Simon JM, Yuan H, Li Z, McConnell MJ, Zylka MJ.
Nat Commun. 2020 Apr 23;11(1):1962. doi: 10.1038/s41467-020-15794-9.
PMID: 3232765

 

Oculodentodigital Dysplasia: A Case Report and Major Review of the Eye and Ocular Adnexa Features of 295 Reported Cases.
Kumar V, Couser NL, Pandya A.
Case Rep Ophthalmol Med. 2020 Apr 4;2020:6535974. doi: 10.1155/2020/6535974. eCollection 2020.
PMID: 32318302

 

Do Groups Have Moral Standing in Unregulated mHealth Research?
Yu JH, Juengst E.
J Law Med Ethics. 2020 Mar;48(1_suppl):122-128. doi: 10.1177/1073110520917037.
PMID: 32342749

 

Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic: CHEST Expert Panel Report.
Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA.
Chest. 2020 Apr 22. pii: S0012-3692(20)30758-3. doi: 10.1016/j.chest.2020.04.020. [Epub ahead of print]
PMID: 32335067