Department of Genetics Publications for July 17th – 30th, 2022

Department of Genetics faculty, postdocs, students and collaborators published 11 papers during July 17^th – 30^th, 2022.

 

The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis. 

Li Y, Misumi I, Shiota T, Sun L, Lenarcic EM, Kim H, Shirasaki T, Hertel-Wulff A, Tibbs T, Mitchell JE, McKnight KL, Cameron CE, Moorman NJ, McGivern DR, Cullen JM, Whitmire JK, Lemon SM.

Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2204511119. doi: 10.1073/pnas.2204511119. Epub 2022 Jul 7.

PMID: 35867748

 

A Multitrait Locus Regulates Sarbecovirus Pathogenesis. 

Schäfer A, Leist SR, Gralinski LE, Martinez DR, Winkler ES, Okuda K, Hawkins PE, Gully KL, Graham RL, Scobey DT, Bell TA, Hock P, Shaw GD, Loome JF, Madden EA, Anderson E, Baxter VK, Taft-Benz SA, Zweigart MR, May SR, Dong S, Clark M, Miller DR, Lynch RM, Heise MT, Tisch R, Boucher RC, Pardo Manuel de Villena F, Montgomery SA, Diamond MS, Ferris MT, Baric RS.

mBio. 2022 Jul 12:e0145422. doi: 10.1128/mbio.01454-22. Online ahead of print.

PMID: 35862771

 

Molecular signatures of in situ to invasive progression for basal-like breast cancers: An integrated mouse model and human DCIS study. 

Thennavan A, Garcia-Recio S, Liu S, He X, Perou CM.

NPJ Breast Cancer. 2022 Jul 18;8(1):83. doi: 10.1038/s41523-022-00450-w.

PMID: 35851387 Free PMC article.

 

Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke. 

Carberry CK, Koval LE, Payton A, Hartwell H, Ho Kim Y, Smith GJ, Reif DM, Jaspers I, Ian Gilmour M, Rager JE.

Environ Int. 2022 Jul 16;167:107419. doi: 10.1016/j.envint.2022.107419. Online ahead of print.

PMID: 35863239

 

Barriers and Facilitators for Population Genetic Screening in Healthy Populations: A Systematic Review. 

Shen EC, Srinivasan S, Passero LE, Allen CG, Dixon M, Foss K, Halliburton B, Milko LV, Smit AK, Carlson R, Roberts MC.

Front Genet. 2022 Jul 4;13:865384. doi: 10.3389/fgene.2022.865384. eCollection 2022.

PMID: 35860476 Free PMC article.

 

Scientists’ Views on Scientific Self-Governance for Human Genome Editing Research. 

Cadigan RJ, Waltz M, Conley JM, Henderson GE, Davis AM, Major R, Juengst ET.

Hum Gene Ther. 2022 Jul 19. doi: 10.1089/hum.2022.087. Online ahead of print.

PMID: 35850532

 

Analysis of Epigenetic Age Acceleration and Healthy Longevity Among Older US Women. 

Jain P, Binder AM, Chen B, Parada H Jr, Gallo LC, Alcaraz J, Horvath S, Bhatti P, Whitsel EA, Jordahl K, Baccarelli AA, Hou L, Stewart JD, Li Y, Justice JN, LaCroix AZ.

JAMA Netw Open. 2022 Jul 1;5(7):e2223285. doi: 10.1001/jamanetworkopen.2022.23285.

PMID: 35895062

 

A multi-omic dissection of super-enhancer driven oncogenic gene expression programs in ovarian cancer. 

Kelly MR, Wisniewska K, Regner MJ, Lewis MW, Perreault AA, Davis ES, Phanstiel DH, Parker JS, Franco HL.

Nat Commun. 2022 Jul 22;13(1):4247. doi: 10.1038/s41467-022-31919-8.

PMID: 35869079 Free PMC article.

 

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program. 

DiCorpo D, Gaynor SM, Russell EM, Westerman KE, Raffield LM, Majarian TD, Wu P, Sarnowski C, Highland HM, Jackson A, Hasbani NR, de Vries PS, Brody JA, Hidalgo B, Guo X, Perry JA, O’Connell JR, Lent S, Montasser ME, Cade BE, Jain D, Wang H, D’Oliveira Albanus R, Varshney A, Yanek LR, Lange L, Palmer ND, Almeida M, Peralta JM, Aslibekyan S, Baldridge AS, Bertoni AG, Bielak LF, Chen CS, Chen YI, Choi WJ, Goodarzi MO, Floyd JS, Irvin MR, Kalyani RR, Kelly TN, Lee S, Liu CT, Loesch D, Manson JE, Minster RL, Naseri T, Pankow JS, Rasmussen-Torvik LJ, Reiner AP, Reupena MS, Selvin E, Smith JA, Weeks DE, Xu H, Yao J, Zhao W, Parker S, Alonso A, Arnett DK, Blangero J, Boerwinkle E, Correa A, Cupples LA, Curran JE, Duggirala R, He J, Heckbert SR, Kardia SLR, Kim RW, Kooperberg C, Liu S, Mathias RA, McGarvey ST, Mitchell BD, Morrison AC, Peyser PA, Psaty BM, Redline S, Shuldiner AR, Taylor KD, Vasan RS, Viaud-Martinez KA, Florez JC, Wilson JG, Sladek R, Rich SS, Rotter JI, Lin X, Dupuis J, Meigs JB, Wessel J, Manning AK.

Commun Biol. 2022 Jul 28;5(1):756. doi: 10.1038/s42003-022-03702-4.

PMID: 35902682

 

Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward. 

Beierle JA, Yao EJ, Goldstein SI, Lynch WB, Scotellaro JL, Shah AA, Sena KD, Wong AL, Linnertz CL, Averin O, Moody DE, Reilly CA, Peltz G, Emili A, Ferris MT, Bryant CD.

J Pharmacol Exp Ther. 2022 Aug;382(2):167-180. doi: 10.1124/jpet.122.001217. Epub 2022 Jun 10.

PMID: 35688478

 

Growth in individuals with attenuated mucopolysaccharidosis type I during untreated and treated periods: Data from the MPS I registry. 

Polgreen LE, Bay L, Clarke LA, Guffon N, Jones SA, Muenzer J, Flores AL, Wilson K, Viskochil D.

Am J Med Genet A. 2022 Jul 23. doi: 10.1002/ajmg.a.62910. Online ahead of print.

PMID: 35869927