Department of Genetics Publications for June 23rd – July 6th, 2024

Department of Genetics faculty, postdocs, students and collaborators published 12 papers during June 23rd – July 6th, 2024.

 

Proteome-wide association study using cis and trans variants and applied to blood cell and lipid-related traits in the Women’s Health Initiative study. 

Chen BD, Lee C, Tapia AL, Reiner AP, Tang H, Kooperberg C, Manson JE, Li Y, Raffield LM.

Genet Epidemiol. 2024 Jun 28. doi: 10.1002/gepi.22578. Online ahead of print.

PMID: 38940271

 

A 44-Nucleotide Region in the Chikungunya Virus 3′ UTR Dictates Viral Fitness in Disparate Host Cells. 

Ander SE, Carpentier KS, Sanders W, Lucas CJ, Jolly AJ, Johnson CN, Hawman DW, Heise MT, Moorman NJ, Morrison TE.

Viruses. 2024 May 28;16(6):861. doi: 10.3390/v16060861.

PMID: 38932154

 

Genomic investigation of bone tuberculosis highlighted the role of subclinical pulmonary tuberculosis in transmission. 

Yin J, Yan G, Qin L, Zhu C, Fan J, Li Y, Jia J, Wu Z, Jiang H, Khan MT, Wu J, Chu N, Takiff HE, Gao Q, Qin S, Liu Q, Li W.

Tuberculosis (Edinb). 2024 Jun 13;148:102534. doi: 10.1016/j.tube.2024.102534. Online ahead of print.

PMID: 38909563

 

Auto-loaded TRAIL-exosomes derived from induced neural stem cells for brain cancer therapy. 

Zhang X, Taylor H, Valdivia A, Dasari R, Buckley A, Bonacquisti E, Nguyen J, Kanchi K, Corcoran DL, Herring LE, Steindler DA, Baldwin A, Hingtgen S, Satterlee AB.

J Control Release. 2024 Jun 26;372:433-445. doi: 10.1016/j.jconrel.2024.06.048. Online ahead of print.

PMID: 38908756

 

Genome-Wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome. 

Tsetsos F, Topaloudi A, Jain P, Yang Z, Yu D, Kolovos P, Tumer Z, Rizzo R, Hartmann A, Depienne C, Worbe Y, Müller-Vahl KR, Cath DC, Boomsma DI, Wolanczyk T, Zekanowski C, Barta C, Nemoda Z, Tarnok Z, Padmanabhuni SS, Buxbaum JD, Grice D, Glennon J, Stefansson H, Hengerer B, Yannaki E, Stamatoyannopoulos JA, Benaroya-Milshtein N, Cardona F, Hedderly T, Heyman I, Huyser C, Mir P, Morer A, Mueller N, Munchau A, Plessen KJ, Porcelli C, Roessner V, Walitza S, Schrag A, Martino D; PGC TS Working Group; TSAICG; TSGeneSEE Initiative; EMTICS Collaborative Group; TS-EUROTRAIN Network; TIC Genetics Collaborative Group; Tischfield JA, Heiman GA, Willsey AJ, Dietrich A, Davis LK, Crowley JJ, Mathews CA, Scharf JM, Georgitsi M, Hoekstra PJ, Paschou P.

Biol Psychiatry. 2024 Jul 15;96(2):114-124. doi: 10.1016/j.biopsych.2023.01.023. Epub 2023 Feb 2.

PMID: 36738982

 

Urinary metabolite concentrations of phthalate and plasticizers in infancy and childhood in the UNC Baby Connectome Project. 

Thistle JE, Liu CW, Rager JE, Singer AB, Chen D, Manley CK, Piven J, Gilmore J, Keil AP, Starling AP, Zhu H, Lin W, Lu K, Engel SM.

Environ Res. 2024 Jun 26:119467. doi: 10.1016/j.envres.2024.119467. Online ahead of print.

PMID: 38942256

 

Advancing microbial production through artificial intelligence-aided biology. 

Gong X, Zhang J, Gan Q, Teng Y, Hou J, Lyu Y, Liu Z, Wu Z, Dai R, Zou Y, Wang X, Zhu D, Zhu H, Liu T, Yan Y.

Biotechnol Adv. 2024 Jun 24;74:108399. doi: 10.1016/j.biotechadv.2024.108399. Online ahead of print.

PMID: 38925317 Review.

 

Amniocentesis in pregnancies at or beyond 24 weeks: An international multicenter study. 

Zemet R, Ali Maktabi M, Tinfow A, Giordano JL, Heisler TM, Yan Q, Plaschkes R, Stokes J, Walsh JM, Corcoran S, Schindewolf E, Miller K, Talati AN, Miller KA, Blakemore K, Swanson K, Ramm J, Bedei I, Sparks TN, Jelin AC, Vora NL, Gebb JS, Crosby DA, Berkenstadt M, Weisz B, Wapner RJ, VAN DEN Veyver IB.

Am J Obstet Gynecol. 2024 Jun 22:S0002-9378(24)00693-8. doi: 10.1016/j.ajog.2024.06.025. Online ahead of print.

PMID: 38914189

 

Loss of Slc35a2 alters development of the mouse cerebral cortex. 

Elziny S, Sran S, Yoon H, Corrigan RR, Page J, Ringland A, Lanier A, Lapidus S, Foreman J, Heinzen EL, Iffland P, Crino PB, Bedrosian TA.

Neurosci Lett. 2024 Jun 21:137881. doi: 10.1016/j.neulet.2024.137881. Online ahead of print.

PMID: 38909838

 

A genome-wide association study of alloimmunization in the TOPMed OMG-SCD cohort identifies a locus on chromosome 12. 

Sun Q, Karafin MS, Garrett ME, Li Y, Ashley-Koch A, Telen MJ.

Transfusion. 2024 Jul 5. doi: 10.1111/trf.17944. Online ahead of print.

PMID: 38966903

 

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication. 

Ong HW, Yang X, Smith JL, Dickmander RJ, Brown JW, Havener TM, Taft-Benz S, Howell S, Sanders MK, Capener JL, Couñago RM, Chang E, Krämer A, Moorman NJ, Heise M, Axtman AD, Drewry DH, Willson TM.

J Med Chem. 2024 Jul 3. doi: 10.1021/acs.jmedchem.4c00962. Online ahead of print.

PMID: 38959455

 

Improving laboratory animal genetic reporting: LAG-R guidelines. 

Teboul L, Amos-Landgraf J, Benavides FJ, Birling MC, Brown SDM, Bryda E, Bunton-Stasyshyn R, Chin HJ, Crispo M, Delerue F, Dobbie M, Franklin CL, Fuchtbauer EM, Gao X, Golzio C, Haffner R, Hérault Y, Hrabe de Angelis M, Lloyd KCK, Magnuson TR, Montoliu L, Murray SA, Nam KH, Nutter LMJ, Pailhoux E, Pardo Manuel de Villena F, Peterson K, Reinholdt L, Sedlacek R, Seong JK, Shiroishi T, Smith C, Takeo T, Tinsley L, Vilotte JL, Warming S, Wells S, Whitelaw CB, Yoshiki A; Asian Mouse Mutagenesis Resource Association; CELPHEDIA infrastructure; INFRAFRONTIER consortium; International Mammalian Genome Society; International Mouse Phenotyping Consortium; International Society for Transgenic Technologies; Mutant Mouse Resource and Research Centers; Phenomics Australia; RRRC- Rat Resource and Research Center; Pavlovic G.

Nat Commun. 2024 Jul 2;15(1):5574. doi: 10.1038/s41467-024-49439-y.

PMID: 38956430 Free PMC article. Review.