Department of Genetics faculty, postdocs, students and collaborators published twelve papers during March 8-21, 2020.

 

HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Kalisz M, Bernardo E, Beucher A, Maestro MA, Del Pozo N, Millán I, Haeberle L, Schlensog M, Safi SA, Knoefel WT, Grau V, de Vas M, Shpargel KB, Vaquero E, Magnuson T, Ortega S, Esposito I, Real FX, Ferrer J.
EMBO J. 2020 Mar 10:e102808. doi: 10.15252/embj.2019102808. [Epub ahead of print]
PMID: 32154941

 

Cross Modality Microscopy Segmentation via Adversarial Adaptation.
Guo Y, Wang Q, Krupa O, Stein J, Wu G, Bradford K, Krishnamurthy A.
Bioinform Biomed Eng (2019). 2019 May;11466:469-478. doi: 10.1007/978-3-030-17935-9_42. Epub 2019 Apr 13.
PMID: 32154516

 

A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles.
Sey NYA, Hu B, Mah W, Fauni H, McAfee JC, Rajarajan P, Brennand KJ, Akbarian S, Won H.
Nat Neurosci. 2020 Mar 9. doi: 10.1038/s41593-020-0603-0. [Epub ahead of print]
PMID: 32152537

 

Projected t-SNE for batch correction.
Aliverti E, Tilson J, Filer DL, Babcock B, Colaneri A, Ocasio J, Gershon TR, Wilhelmsen KC, Dunson DB.
Bioinformatics. 2020 Mar 16. pii: btaa189. doi: 10.1093/bioinformatics/btaa189. [Epub ahead of print]
PMID: 3217624

 

Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics.
Hodonsky CJ, Baldassari AR, Bien SA, Raffield LM, Highland HM, Sitlani CM, Wojcik GL, Tao R, Graff M, Tang W, Thyagarajan B, Buyske S, Fornage M, Hindorff LA, Li Y, Lin D, Reiner AP, North KE, Loos RJF, Kooperberg C, Avery CL.
BMC Genomics. 2020 Mar 14;21(1):228. doi: 10.1186/s12864-020-6626-9.
PMID: 32171239

 

Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy.
Bhatt AP, Pellock SJ, Biernat KA, Walton WG, Wallace BD, Creekmore BC, Letertre MM, Swann JR, Wilson ID, Roques JR, Darr DB, Bailey ST, Montgomery SA, Roach JM, Azcarate-Peril MA, Sartor RB, Gharaibeh RZ, Bultman SJ, Redinbo MR.
Proc Natl Acad Sci U S A. 2020 Mar 13. pii: 201918095. doi: 10.1073/pnas.1918095117. [Epub ahead of print]
PMID: 3217000

 

SAME-clustering: Single-cell Aggregated Clustering via Mixture Model Ensemble.
Huh R, Yang Y, Jiang Y, Shen Y, Li Y.
Nucleic Acids Res. 2020 Jan 10;48(1):86-95. doi: 10.1093/nar/gkz959.
PMID: 31777938

 

Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages.
Fang Y, Coelho MA, Shu H, Schotanus K, Thimmappa BC, Yadav V, Chen H, Malc EP, Wang J, Mieczkowski PA, Kronmiller B, Tyler BM, Sanyal K, Dong S, Nowrousian M, Heitman J.
PLoS Genet. 2020 Mar 9;16(3):e1008646. doi: 10.1371/journal.pgen.1008646. [Epub ahead of print]
PMID: 32150559

 

Lymphatic Programing and Specialization in Hybrid Vessels.
Pawlak JB, Caron KM.
Front Physiol. 2020 Feb 20;11:114. doi: 10.3389/fphys.2020.00114. eCollection 2020. Review.
PMID: 3215342

 

Pilot Study of [<sup>18</sup>F] Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)/Magnetic Resonance Imaging (MRI) for Staging of Muscle-invasive Bladder Cancer (MIBC).
Eulitt PJ, Altun E, Sheikh A, Wong TZ, Woods ME, Rose TL, Wallen EM, Pruthi RS, Smith AB, Nielsen ME, Whang YE, Kim WY, Godley PA, Basch EM, David GU, Ramirez J, Deal AM, Rathmell WK, Chen RC, Bjurlin MA, Lin W, Lee JK, Milowsky MI.
Clin Genitourin Cancer. 2020 Mar 5. pii: S1558-7673(20)30042-2. doi: 10.1016/j.clgc.2020.02.008. [Epub ahead of print]
PMID: 3214736

 

Rif1 Functions in a Tissue-Specific Manner To Control Replication Timing Through Its PP1-binding Motif.
Armstrong RL, Das S, Hill CA, Duronio RJ, Nordman JT.
Genetics. 2020 Mar 6. pii: genetics.303155.2020. doi: 10.1534/genetics.120.303155. [Epub ahead of print]
PMID: 32144132

 

Editorial: Molecular Mechanisms in Stress and Trauma Related Disorders.
Zannas AS, Stein MB, Chrousos GP.
Front Psychiatry. 2020 Mar 3;11:103. doi: 10.3389/fpsyt.2020.00103. eCollection 2020. No abstract available.
PMID: 32194451