Department of Genetics Publications March 13th – 26th, 2022

Department of Genetics faculty, postdocs, students and collaborators published 11 papers during March 13^th – 26^th 2022.

 

eQTL mapping using allele-specific count data is computationally feasible, powerful, and provides individual-specific estimates of genetic effects. 

Zhabotynsky V, Huang L, Little P, Hu YJ, Pardo-Manuel de Villena F, Zou F, Sun W.

PLoS Genet. 2022 Mar 14;18(3):e1010076. doi: 10.1371/journal.pgen.1010076. Online ahead of print.

PMID: 35286297

 

Bioorthogonal Chemical Epigenetic Modifiers Enable Dose-Dependent CRISPR Targeted Gene Activation in Mammalian Cells. 

Lu D, Foley CA, Birla SV, Hepperla AJ, Simon JM, James LI, Hathaway NA.

ACS Synth Biol. 2022 Mar 18. doi: 10.1021/acssynbio.1c00606. Online ahead of print.

PMID: 35302756

 

Elevated common variant genetic risk for tourette syndrome in a densely-affected pedigree. 

Halvorsen M, Szatkiewicz J, Mudgal P, Yu D; Psychiatric Genomics Consortium TS/OCD Working Group, Nordsletten AE, Mataix-Cols D, Mathews CA, Scharf JM, Mattheisen M, Robertson MM, McQuillin A, Crowley JJ.

Mol Psychiatry. 2021 Dec;26(12):7522-7529. doi: 10.1038/s41380-021-01277-w. Epub 2021 Sep 15.

PMID: 34526668 Free PMC article.

 

A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam. 

Campbell C, McCormack M, Patel S, Stapleton C, Bobbili D, Krause R, Depondt C, Sills GJ, Koeleman BP, Striano P, Zara F, Sander JW, Lerche H, Kunz WS, Stefansson K, Stefansson H, Doherty CP, Heinzen EL, Scheffer IE, Goldstein DB, O’Brien T, Cotter D, Berkovic SF; EpiPGX Consortium, Sisodiya SM, Delanty N, Cavalleri GL.

Epilepsia. 2022 Mar 17. doi: 10.1111/epi.17228. Online ahead of print.

PMID: 35298028

 

Cross-trait prediction accuracy of summary statistics in genome-wide association studies. 

Zhao B, Zou F, Zhu H.

Biometrics. 2022 Mar 12. doi: 10.1111/biom.13661. Online ahead of print.

PMID: 35278218

 

Differences in the microbial profiles of early stage endometrial cancers between Black and White women. 

Hawkins GM, Burkett WC, McCoy AN, Nichols HB, Olshan AF, Broaddus R, Merker JD, Weissman B, Brewster WR, Roach J, Keku TO, Bae-Jump V.

Gynecol Oncol. 2022 Mar 8:S0090-8258(22)00142-1. doi: 10.1016/j.ygyno.2022.02.021. Online ahead of print.

PMID: 35277280

 

TWO-SIGMA-G: a new competitive gene set testing framework for scRNA-seq data accounting for inter-gene and cell-cell correlation. 

Van Buren E, Hu M, Cheng L, Wrobel J, Wilhelmsen K, Su L, Li Y, Wu D.

Brief Bioinform. 2022 Mar 24:bbac084. doi: 10.1093/bib/bbac084. Online ahead of print.

PMID: 35325048

 

Nematode chromosomes. 

Carlton PM, Davis RE, Ahmed S.

Genetics. 2022 Mar 22:iyac014. doi: 10.1093/genetics/iyac014. Online ahead of print.

PMID: 35323874

 

Genetic and Epigenetic Inheritance at Telomeres. 

Lister-Shimauchi EH, McCarthy B, Lippincott M, Ahmed S.

Epigenomes. 2022 Mar 16;6(1):9. doi: 10.3390/epigenomes6010009.

PMID: 35323213 Review.

 

Gene expression changes following chronic antipsychotic exposure in single cells from mouse striatum. 

Abrantes A, Giusti-Rodriguez P, Ancalade N, Sekle S, Basiri ML, Stuber GD, Sullivan PF, Hultman R.

Mol Psychiatry. 2022 Mar 23. doi: 10.1038/s41380-022-01509-7. Online ahead of print.

PMID: 35322200

 

Quality of care metrics for patients with inborn errors of metabolism. 

Adams MC, Jalazo ER, Hildebrandt CC, Wong J, Mascaro-Deen SJ, Berg JS.

Mol Genet Metab. 2022 Mar 15:S1096-7192(22)00156-1. doi: 10.1016/j.ymgme.2022.03.005. Online ahead of print.

PMID: 35314103