The UNC Kidney Center is a Center for Excellence for Glomerular Disease and Vasculitis, providing clinical care for patients and leading research studies.

Clinical Care: Vasculitis and GN Providers

	Ron Falk, MD  Nan and Hugh Cullman Eminent Professor; Director, UNC Kidney Center  Specialty Areas: Glomerular disease; Lupus; Vasculitis; ANCA-mediated Vasculitis
	Dhruti Chen, MD Associate Professor of Medicine Specialty Areas: Acute and chronic kidney diseases with a special interest in glomerulonephritis including ANCA-vasculitis, minimal change disease, and other nephrotic syndromes.
	Vimal Derebail, MD, MPH Associate Professor of Medicine Specialty Areas: Glomerular disease, nephrotic syndrome, vasculitis (primary focus: ANCA vasculitis), thrombotic complications in glomerulonephritis
	Keisha Gibson, MD Associate Professor of Medicine and Pediatrics Specialty Areas: Pediatric Nephrology
	Koyal Jain, MD Assistant Professor of Medicine Specialty Areas: Glomerular disease, vasculitis (primary focus: ANCA vasculitis), lupus nephritis
	Amy Mottl, MD, MPH Associate Professor of Medicine Specialty Areas: Glomerular Disease, Nephrotic Syndrome, FSGS, Minimal Change Disease, Membranous Nephropathy
	Manish Saha, MD Assistant Professor of Medicine Specialty Areas: Glomerular diseases, (primary focus: IgA Nephropathy), ANCA-vasculitis, lupus nephritis, thrombotic microangiopathy, nephrotic syndrome

Participate in Clinical Trials

Visit studies page to view information and learn how to participate.

Observational Research Studies

ANCA Glomerulonephritis: From Molecules to Man

Funding Source: NIDDK/NIH

This program project consists of three projects and two cores focusing on a broad spectrum of research on anti-neutrophil cytoplasmic autoantibody (ANCA) necrotizing and crescentic glomerulonephritis and small vessel vasculitis (SVV). The scope of the investigation and the diversity of the investigators allow for an integrated evaluation of myeloperoxidase (MPO) and proteinase 3 (PR3) autoimmune response. Core A gathers biologic samples and clinical information from patients with ANCA glomerulonephritis, as well as from other individuals as needed for other disease and healthy controls.

Cure Glomerulonephropathy (CureGN) Study

Funding Source: NIDDK/NIH

CureGN is a multicenter cohort study of glomerular disease patients funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes for Health (NIH).The CureGN project will study 2,400 children and adults with the following glomerular diseases: minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), and IgA nephropathy (IGAN).Participants will be followed longitudinally to better understand the causes of disease, response to therapy, and disease progression, with the ultimate objective to cure glomerulonephropathy.

Nephrotic Syndrome Study Network (NEPTUNE)

Funding Source: Office of Rare Diseases/NephCure/NIDDK/NIH

NEPTUNE is multi-center, multidisciplinary research and education platform that brings together clinical and translational scientists and two lay research and patient education foundations to better study focal segmental glomerulosclerosis, membranous nephropathy and minimal change disease. The goal of this project is to assemble and characterize an incident population of kidney disease patients into a prospective research cohort made available to network and external investigators to conduct clinical and translational research aimed at new preventative, diagnostic and therapeutic targets for glomerular disease causing nephrotic syndrome.