March 26, 2020
ASH Journal, Blood article by Alisa S Wolberg, PhD
High fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice Abstract: Obesity is a prevalent prothrombotic risk factor marked by enhanced fibrin formation and suppressed fibrinolysis. Fibrin both promotes thrombotic events and drives obesity pathophysiology, but a lack of essential analytical tools has left fibrinolytic mechanisms affected by obesity poorly defined. Using a …