News Archives | Page 12 of 18 | UNC Blood Research Center

photo of matthew karafin, smiling in a suit

The focus of the grant is to investigate red blood cell alloimmunization risk using the REDS-III databases. Red blood cell (RBC) alloimmunization is a leading cause of morbidity and mortality in transfusion and pregnancy settings, resulting in hemolytic reactions and other adverse sequelae such as hemolytic disease of the fetus and newborn. Alloimmunization occurs in …

Dr. Patrick Ellsworth has been awarded the Access to Insight 2022 Basic Research Grant, totaling 63,000 Euros! This was a competitive grant with international applicants. Dr. Ellsworth’s project is titled “Mechanistic Investigation of Factor IX/IXa Synergy with Emicizumab” and he will be working with Dr. Monroe here of the BRC and Dr. Maureane Hoffman at Duke …

Effective July 1, 2022, Dr. Alisa Wolberg began service as the new Chair of the Hemostasis, Thrombosis, Blood Cells, and Transfusion study section of the NHLBI. She will serve a 2-year term in this role. Congratulations, Dr. Wolberg!

“A gene therapy clinical trial for hemophilia shows promise and could be approved by the FDA later this year — a feat made possible, in part, by UNC-Chapel Hill’s 70-year-old research program.” Click here to read the article.

Click here to read the June 2022 Newsletter

Research performed at the BRC will be well represented at the 30th Congress of the International Society on Thrombosis and Haemostasis meeting in London, UK from July 9-13. A list of scheduled oral presentations and posters is included at this link.

Erica Sparkenbaugh, PhD, has been awarded a NC TRaCS $2K Pilot Grant for her study “Evaluation of Pre-thrombotic Markers in Female Patients with Sickle Cell Disease on Hormonal Contraception”. Congrats, Erica!

Woosuk Steve Hur, a postdoctoral fellow in the Flick Lab, has been awarded a Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship. This award covers salary support and provides funds for travel for 2 years.

Katharine King, a third year undergraduate from the biology department working in Dr. Flick’s lab, gave an invited oral presentation at the Nutrition and Obesity Research Center (NORC) Symposium last week. Her presentation was entitled: “Elimination of fibrin(ogen)-aMb2-binding function, but not fibrinogen deficiency, protects against obesity and metabolic syndrome” Katie won the undergraduate student oral …

On April 1st, 2022, Nigel Mackman, PhD presented the inaugural J. Evans Sadler Lectureship – ‘Mechanisms of Cancer-Associated Thrombosis’

Platelets are critical in hemostasis and a major contributor to arterial thrombosis (AT). (Pre)clinical studies suggest platelets also contribute to venous thrombosis (VT), but the mechanisms are largely unknown. Jean Marie Mwiza, a graduate student in the Pathology department jointly supervised by Drs. Alisa Wolberg and Wolfgang Bergmeier, recently spear-headed an international team of investigators …

Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by the small GTPase Rap1 on …

Category: News

Matt Karafin, MD is a Collaborating Investigator on a Recently Awarded Multi-Institution R21 Grant From the NIH-NHBLI

Patrick Ellsworth, MD Awarded Research Grant

Alisa Wolberg, PhD New Chair of HTBT Study Section

UNC Contribution to Gene Therapy in Hemophilia Highlighted by Endeavors Magazine

BRC Newsletter – June 2022

Blood Research Center Members to Present Their Research at Upcoming ISTH Meeting

Erica Sparkenbaugh, PhD Awarded NC TRaCS $2K Pilot Grant

Woosuk Steve Hur, PhD Awarded a Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship

Katharine King Wins Undergraduate Student Oral Presentation Award

Nigel Mackman, PhD Presented the Inaugural J. Evan Sadler Lectureship

Jean Marie Mwiza Published in the Journal Blood

Dr. Robert Lee, Bergmeier Lab Published: Journal of Clinical Investigation Insight