December 21, 2022
Brandi Reeves, MD was awarded a Core Facilities voucher to characterize neurobehavioral changes in a mouse model of polycythemia vera. Neurobehavioral complaints are common in patients with polycythemia vera (PV), with 75% of patients reporting symptoms. Fatigue, inactivity, and concentration difficulties are the most common and severe symptoms experienced by PV patients and result in …
December 5, 2022
On December 1st, 2022, Yohei Hisada presented at a virtual educational “Bloody Thursday” session to the Department of Medicine at the Medical University of Vienna. The title of the presentation was “Insights into the pathogenesis of cancer-associated venous thromboembolism”. Well done, Dr. Hisada!
December 1, 2022
Click here to read the December 2022 Newsletter
December 1, 2022
Steve Hur, PhD was awarded the JTH Editors Award for his recent article, Elimination of fibrin polymer formation or crosslinking, but not fibrinogen deficiency, is protective against diet-induced obesity and associated pathologies. From ISTH: “The JTH Editors’ Awards recognize the best papers by early career investigators. The award consists of a certificate, to be awarded …
November 17, 2022
Click the link below to review the ASH abstracts spreadsheet featuring UNC Hematology and BRC members! 2022 ASH UNC Presentations and Abstracts
October 6, 2022
An abstract submitted by Steven Grover, PhD on work conducted in the laboratory of Nigel Mackman, PhD was selected for presentation in the plenary scientific session at the 64th American Society of Hematology annual meeting. While conducting this work Dr Grover was supported by the UNC Blood Research Center T32 Post-Doctoral Training Program in Benign …
October 3, 2022
Click here to read the October 2022 Newsletter
September 19, 2022
In the NIH-funded ‘American Trial Using Tranexamic Acid in Thrombocytopenia (A-TREAT)’ trial, UNC was one of 3 participating clinical centers to enroll patients with platelet transfusion-dependence due to therapy for hematologic malignancies. Between 2016 and 2020, 337 patients were randomized in a double blind fashion to tranexamic acid (TXA) or placebo. Ultimately, no benefit of …
August 20, 2022
Matthew Flick, PhD was recently awarded a NIH U01 grant, which is part of the Pancreatic Ductal Adenocarcinoma (PDAC) Stromal Reprogramming Consortium (PSRC). This is an MPI award that Dr. Flick received with collaborators Bumsoo Han, PhD at Purdue University and Melissa Fishel, PhD at the Indiana University School of Medicine. The title of the …
July 28, 2022
Drs. Raj Kasthuri and Yara Park of the UNC BRC, along with multiple alumni of the UNC hematology and transfusion medicine fellowships, co-authored a multi-institutional investigation into the role of race in the response of TTP patients to rituximab that has been accepted for publication in Blood. The study included 645 TTP patients from …
July 26, 2022
The focus of the grant is to investigate red blood cell alloimmunization risk using the REDS-III databases. Red blood cell (RBC) alloimmunization is a leading cause of morbidity and mortality in transfusion and pregnancy settings, resulting in hemolytic reactions and other adverse sequelae such as hemolytic disease of the fetus and newborn. Alloimmunization occurs in …
July 22, 2022
Dr. Patrick Ellsworth has been awarded the Access to Insight 2022 Basic Research Grant, totaling 63,000 Euros! This was a competitive grant with international applicants. Dr. Ellsworth’s project is titled “Mechanistic Investigation of Factor IX/IXa Synergy with Emicizumab” and he will be working with Dr. Monroe here of the BRC and Dr. Maureane Hoffman at Duke …