News Archives | Page 3 of 18 | UNC Blood Research Center

UNC Hem/Onc Fellow Sam Short, MD and collaborators/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation. Improving stroke risk prediction in atrial fibrillation with circulating biomarkers: the CHA2DS2-VASc–Biomarkers model (DOI: 10.1016/j.jtha.2025.06.007) Circulating biomarkers and ischemic stroke risk in adults with atrial fibrillation taking anticoagulation: the Reasons for Geographic And Racial …

Karin Leiderman, PhD and Dougald Monroe, PhD published in JTH. Mathematical analysis of emicizumab: affinity-driven complex formation and lipid-surface reactions. This study aimed to investigate emicizumab’s lipid-surface dependent mechanisms through mathematical modeling and biochemical assays. Read more here

Erica Sparkenbaugh, PhD appointed the co-chair of the 2029 HTRS Scientific Symposium Planning Committee We are excited to announce the Planning Committee for the HTRS 2027 Scientific Symposium, a dynamic three-day scientific conference dedicated to the advancement of clinical, translational, and discovery-based science research related to disorders of hemostasis and thrombosis. Meet …

Dr Monroe and colleagues published a study on the role of plasma inhibitors in regulating thrombin levels. Dougald Monroe, professor in the UNC Division of Hematology, and colleagues Allen Ma and Maureane Hoffman published their study on the contribution of four plasma inhibitors in regulating thrombin generation. The work was published in Blood Vessels, Thrombosis, …

View BRC August 2025 Newsletter August 2025 Newsletter

photo of matthew karafin, smiling in a suit

Matthew Karafin published the initial results of his prospective randomized clinical trial in JCI. Authors: Matthew S. Karafin, Abby S. Grier, Ross M. Fasano, Anton Ilich, David Wichlan, Ada Chang, Sonjile M. James, Hailly E. Butler, Oleg Kolupaev, Melissa C. Caughey, Daniel Stephenson, Julie A. Reisz, Nigel S. Key, Joshua J. Field, Jane A. Little, Steven L. Spitanik, …

Please join us for our Fall 2025 Blood Research Center Seminar Series, happening at 11am. Follow us on Linkedin for more information

Kylie Hutchison, a rising 2nd year PhD student within the Pathobiology and Translational Science program, was accepted into the UNC Certificate Program in Translational Medicine and selected as 1 of 4 trainees to receive funding from the certificate’s T32 training grant from the National Institute for General Medical Sciences (NIGMS) (NIH T32GM122741). This certificate program provides specialized …

Published article in Biophys Journal: Modeling platelet P2Y1/12 pathway to integrin activation. Authors: Patel KB, Bergmeier W, Fogelson AL.

Published article in JTH: Lack of overt bleeding or platelet dysfunction in a mouse model of vascular Ehlers-Danlos syndrome. Authors: Lee RH, Jones SR, Martyanov AA, Vander Ploeg MR, Sagues CF, Bergmeier W.

UNC’s Vital Signs highlighted work from the Wolberg laboratory (https://news.unchealthcare.org/2025/05/unc-study-offers-new-hope-for-safer-bleeding-treatments/) that is currently in press in Blood (https://ashpublications.org/blood/article/doi/10.1182/blood.2025028680/537391/Plasminogen-activation-and-plasmin-activity-are). This work showed that plasminogen activation and activity are not required to prevent venous thrombosis/thromboembolism, and suggests that use of antifibrinolytic therapy to decrease bleeding is not expected to increase thrombosis risk. This work was first authored …

Dr. Yaqiu Sang, a postdoctoral fellow in Dr. Wolberg’s laboratory was featured in the Brinkhous Bulletin, the Department of Pathology and Laboratory Medicine’s monthly newsletter that reports exciting developments in the department. Dr. Sang was highlighted for her her contributions to the Wolberg lab including her recent paper published in Blood (https://ashpublications.org/blood/article/doi/10.1182/blood.2025028680/537391/Plasminogen-activation-and-plasmin-activity-are).

Category: News

Sam Short, MD and collaborators/mentors from the REGARDS study published two papers in JTH about stroke risk in atrial fibrillation.

Karin Leiderman, PhD and Dougald Monroe, PhD published in JTH

Erica Sparkenbaugh, PhD appointed the co-chair of the 2029 HTRS Scientific Symposium Planning Committee

Dougald Monroe, PhD, Allen Ma, and Maureane Hoffman, PhD MD, published in Blood Vessels, Thrombosis, & Hemostasis.

BRC August 2025 Newsletter

Matthew Karafin, MD MS, published the initial results of his prospective randomized clinical trial in JCI.

Fall 2025 BRC Seminar Series

Kylie Hutchison, was accepted into the UNC Certificate Program in Translational Medicine

Published article in Biophys Journal: Modeling platelet P2Y1/12 pathway to integrin activation.

Published article in JTH: Lack of overt bleeding or platelet dysfunction in a mouse model of vascular Ehlers-Danlos syndrome.

UNC’s Vital Signs highlighted work from the Wolberg laboratory

Dr. Yaqiu Sang, a postdoctoral fellow in Dr. Wolberg’s laboratory was featured in the Brinkhous Bulletin, the Department of Pathology and Laboratory Medicine’s monthly newsletter