
August 14, 2025
BRC August 2025 Newsletter
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August 14, 2025
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August 7, 2025
Matthew Karafin published the initial results of his prospective randomized clinical trial in JCI. Authors: Matthew S. Karafin, Abby S. Grier, Ross M. Fasano, Anton Ilich, David Wichlan, Ada Chang, Sonjile M. James, Hailly E. Butler, Oleg Kolupaev, Melissa C. Caughey, Daniel Stephenson, Julie A. Reisz, Nigel S. Key, Joshua J. Field, Jane A. Little, Steven L. Spitanik, …

July 30, 2025
Please join us for our Fall 2025 Blood Research Center Seminar Series, happening at 11am. Follow us on Linkedin for more information

July 25, 2025
Kylie Hutchison, a rising 2nd year PhD student within the Pathobiology and Translational Science program, was accepted into the UNC Certificate Program in Translational Medicine and selected as 1 of 4 trainees to receive funding from the certificate’s T32 training grant from the National Institute for General Medical Sciences (NIGMS) (NIH T32GM122741). This certificate program provides specialized …

June 10, 2025
Published article in Biophys Journal: Modeling platelet P2Y1/12 pathway to integrin activation. Authors: Patel KB, Bergmeier W, Fogelson AL.

June 10, 2025
Published article in JTH: Lack of overt bleeding or platelet dysfunction in a mouse model of vascular Ehlers-Danlos syndrome. Authors: Lee RH, Jones SR, Martyanov AA, Vander Ploeg MR, Sagues CF, Bergmeier W.

June 5, 2025
UNC’s Vital Signs highlighted work from the Wolberg laboratory (https://news.unchealthcare.org/2025/05/unc-study-offers-new-hope-for-safer-bleeding-treatments/) that is currently in press in Blood (https://ashpublications.org/blood/article/doi/10.1182/blood.2025028680/537391/Plasminogen-activation-and-plasmin-activity-are). This work showed that plasminogen activation and activity are not required to prevent venous thrombosis/thromboembolism, and suggests that use of antifibrinolytic therapy to decrease bleeding is not expected to increase thrombosis risk. This work was first authored …

June 5, 2025
Dr. Yaqiu Sang, a postdoctoral fellow in Dr. Wolberg’s laboratory was featured in the Brinkhous Bulletin, the Department of Pathology and Laboratory Medicine’s monthly newsletter that reports exciting developments in the department. Dr. Sang was highlighted for her her contributions to the Wolberg lab including her recent paper published in Blood (https://ashpublications.org/blood/article/doi/10.1182/blood.2025028680/537391/Plasminogen-activation-and-plasmin-activity-are).

June 5, 2025
Read more on this Case Study An 8-year-old female with sickle cell disease (SCD), hemoglobin SS genotype, global developmental delay, and pica established care shortly after moving from out of state. The patient and her family had been living in a weathered house. The child’s caregiver reported a recent history of weakness in the right …

June 5, 2025
Dr. Alisa Wolberg received 2nd year of NIH R01 for “Interdisciplinary approach to elucidate modifiers of bleeding phenotype in factor XI deficiency”. More information

June 5, 2025
Dr. Matthew Flick received another year of funding from UVA “Novel mechanism underlying fibrinogen biogenesis in the endoplasmic reticulum”, an NIH funded project. NIH RePorter

May 5, 2025
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