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September 10, 2021

Alisa S. Wolberg, PhD, has been selected to deliver the Sol Sherry Distinguished Lecture

Alisa S. Wolberg, PhD, has been selected to deliver the Sol Sherry Distinguished Lecture in Thrombosis at the American Heart Association Scientific Sessions in November, 2021. The Sol Sherry Lectureship honors the founder of the original AHA Council on Thrombosis. The Sherry Lecture is one of three Council on Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) named lectures presented …

August 30, 2021

UNC Blood Research Center is a proud sponsor to the Gordon Research Conference Plasminogen Activation and Extracellular Proteolysis

UNC Blood Research Center’s contribution to research~  BRC member and Conference organizer Dr. Matthew Flick will Chair the conference being held February 6-11, 2022.   Plasminogen Activation and Extracellular Proteolysis, Gordon Research Conference Mechanisms and Therapeutic Targets of Extracellular Proteolysis in Human Disease February 6 – 11, 2022 Apply Now Chairs Matthew Flick and Tetsumei …

August 10, 2021

Robert Lee, PhD: Awarded a 2-year basic science grant from the Ehlers-Danlos Society

Congratulations to Robert Lee, PhD Dr. Lee was awarded a 2-year basic science grant from the Ehlers-Danlos Society entitled “Investigating Intrinsic Platelet Dysfunction in Ehlers-Danlos Syndrome”. The main objective of the project is to understand the contribution of impaired platelet function to bleeding in Ehlers Danlos Syndrome, a group of inherited connective tissue disorders with …

July 26, 2021

Public Health Webinar Series on Blood Disorders: Hereditary Hemorrhagic Telangiectasia in 2021: Diagnosis and Advances in Treatment

Public Health Webinar Series on Blood Disorders BRINGING SCIENCE INTO PRACTICE The Division of Blood Disorders is proud to offer this webinar series, providing evidence-based information on new research, emerging issues of interest in blood disorders, as well as innovative approaches to collaboration. Hereditary Hemorrhagic Telangiectasia in 2021: Diagnosis and Advances in Treatment August 19, …

April 29, 2021

Lancet Haematology Journal Commentary: Sevuparin trial for acute pain in sickle cell disease: the dog that did not bark

We might never know the answer to these specific questions, but we should continue to document realworld findings, particularly regarding the risks and benefits of voxelotor to end-organ function. Building on preclinical models,7 preliminary studies showing preserved or lowered cerebral blood flow,8 together with the results of this study1 and ongoing studies, such as HOPE …

April 8, 2021

Publication news! Plasmin-mediated Cleavage of High Molecular Weight Kininogen Contributes to Acetaminophen-Induced Acute Liver Failure

Michael Henderson, PhD, Key lab of the Blood Research Center has first author publication: Abstract Acetaminophen (APAP)-induced liver injury is associated with activation of coagulation and fibrinolysis. In mice, both tissue factor-dependent thrombin generation and plasmin activity have been shown to promote liver injury after APAP overdose. However, the contribution of the contact and intrinsic …