July 22, 2022
Dr. Patrick Ellsworth has been awarded the Access to Insight 2022 Basic Research Grant, totaling 63,000 Euros! This was a competitive grant with international applicants. Dr. Ellsworth’s project is titled “Mechanistic Investigation of Factor IX/IXa Synergy with Emicizumab” and he will be working with Dr. Monroe here of the BRC and Dr. Maureane Hoffman at Duke …
July 22, 2022
Effective July 1, 2022, Dr. Alisa Wolberg began service as the new Chair of the Hemostasis, Thrombosis, Blood Cells, and Transfusion study section of the NHLBI. She will serve a 2-year term in this role. Congratulations, Dr. Wolberg!
June 16, 2022
“A gene therapy clinical trial for hemophilia shows promise and could be approved by the FDA later this year — a feat made possible, in part, by UNC-Chapel Hill’s 70-year-old research program.” Click here to read the article.
June 3, 2022
Click here to read the June 2022 Newsletter
May 11, 2022
Research performed at the BRC will be well represented at the 30th Congress of the International Society on Thrombosis and Haemostasis meeting in London, UK from July 9-13. A list of scheduled oral presentations and posters is included at this link.
May 4, 2022
Erica Sparkenbaugh, PhD, has been awarded a NC TRaCS $2K Pilot Grant for her study “Evaluation of Pre-thrombotic Markers in Female Patients with Sickle Cell Disease on Hormonal Contraception”. Congrats, Erica!
April 30, 2022
Woosuk Steve Hur, a postdoctoral fellow in the Flick Lab, has been awarded a Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship. This award covers salary support and provides funds for travel for 2 years.
April 27, 2022
Katharine King, a third year undergraduate from the biology department working in Dr. Flick’s lab, gave an invited oral presentation at the Nutrition and Obesity Research Center (NORC) Symposium last week. Her presentation was entitled: “Elimination of fibrin(ogen)-aMb2-binding function, but not fibrinogen deficiency, protects against obesity and metabolic syndrome” Katie won the undergraduate student oral …
April 5, 2022
On April 1st, 2022, Nigel Mackman, PhD presented the inaugural J. Evans Sadler Lectureship – ‘Mechanisms of Cancer-Associated Thrombosis’
April 4, 2022
Platelets are critical in hemostasis and a major contributor to arterial thrombosis (AT). (Pre)clinical studies suggest platelets also contribute to venous thrombosis (VT), but the mechanisms are largely unknown. Jean Marie Mwiza, a graduate student in the Pathology department jointly supervised by Drs. Alisa Wolberg and Wolfgang Bergmeier, recently spear-headed an international team of investigators …
April 4, 2022
Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by the small GTPase Rap1 on …
March 17, 2022
Dr. Nigel Key co-authored a manuscript describing the pivotal multi-center Phase 3 clinical trial of adeno-associated virus 5 (AAV5)- based gene therapy for severe hemophilia A that was published in the New England Journal of Medicine on March 17, 2022. The trial sponsor was Biomarin Pharmaceutical. Of 134 participants with severe hemophilia who were enrolled, …