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Terry Furey and Praveen Sethupathy coauthor a Perspective in Science

Furey and Sethupathy November 15, 2013

The article discusses three reports on DNA variants in the human genome that affect gene regulation epigenetically, via sequence-specific binding-affinity of transcription factors.



Dr. Norman Sharpless appointed director of UNC Lineberger Comprehensive Cancer Center

August 23, 2013

Dr. Sharpless succeeds H. Shelton “Shelley” Earp, MD, as center director effective January 1, 2014. William Roper, MD, MPH, Dean of the School of Medicine, Vice Chancellor for Medical Affairs, and CEO of University of North Carolina Health Care System, announces the appointment of Norman “Ned” Sharpless, MD, as director … Continued



Samir Kelada and Praveen Sethupathy Coauthor New Article in PLoS Pathogens

July 8, 2013

In collaboration with groups at three other institutions, they identified different miRNAs that are critical “regulatory hubs” in the immune response to the parasites Leishmania major and Schistosoma mansoni. Samir and Praveen share first authorship with Isobel Okoye at the National Institute for Medical Research in London. In addition to … Continued



Chuck Perou Receives 2013 Battle Cancer Research Award

June 6, 2013

Chuck has been honored with the 2013 Hyman L. Battle Distinguished Cancer Research Award in recognition of his accomplishments in cancer research. The Battle Distinguished Cancer Research Award, established in 2007 by the Battle Foundation of Rocky Mount, N.C., recognizes exceptional cancer research at the UNC School of Medicine and … Continued



New Publications from Praveen Sethupathy’s Lab

May 22, 2013

A research article highlights a method for prioritizing variants in miRNAs by their functional significance. Two Thematic Reviews are included in a special section of the Journal of Lipid Research. The new research findings include the observation that a variant in the promoter of the miRNA let-7 may contribute to … Continued



Jim Evans publishes Viewpoint article in JAMA

April 29, 2013

The article by Jim Evans discusses the importance of the involvement of knowledgeable health care providers in communicating complex genomic information to patients and research subjects. Jim Evans has published a Viewpoint article in JAMA, with coauthors Amy L. McGuire, JD, PhD, and Laurence B. McCullough, PhD, at the Baylor … Continued



Chuck Perou named as a finalist for the Triangle Business Journal’s 2013 “Health Care Heroes” award

April 26, 2013

Triangle Business Journal on Tuesday unveiled 29 finalists for its 2013 Health Care Heroes Awards. Chuck and colleagues have also recently published an article in The Oncologist The Health Care Heroes finalists were honored at an awards dinner on March 21 at the Renaissance Raleigh North Hills Hotel. “Our winners … Continued



Karen Mohlke has paper published in Nature Genetics

April 17, 2013

Karen Mohlke is corresponding author on a paper reporting low-frequency variants in three new genes associated with abnormal insulin production or processing. Karen Mohlke is corresponding author on a paper reporting low-frequency variants in three new genes associated with abnormal insulin production or processing. This work, which was done in … Continued



Diabetes investigation in rats makes editor’s pick in APS journal.

April 17, 2013

An investigation into diabetes-related outcomes in a rat model, with senior author William Valdar, PhD, assistant professor of genetics at UNC, and first author Leah Solberg Woods, PhD, from the Medical College of Wisconsin, has made the editor’s pick in this month’s Physiological Genomics, a journal of the American Physiological … Continued



New mouse model to visualize tumor growth

April 17, 2013

Ned Sharpless and colleagues have developed a mouse model that makes it possible to visualize tumor growth by means of a “knocked-in” p16 gene linked to a luciferase reporter. This work is described in a paper in the January 17, 2013, issue of Cell. Ned was interviewed about the study … Continued



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