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UNC Genetics PublicationsDepartment of Genetics faculty, postdocs, students and collaborators published seven papers during October 4-10, 2020.

 

 

 

Discovery of ongoing selective sweeps within Anopheles mosquito populations using deep learning. 

Xue AT, Schrider DR, Kern AD; Ag1000G Consortium.

Mol Biol Evol. 2020 Oct 6:msaa259. doi: 10.1093/molbev/msaa259. Online ahead of print.

PMID: 33022051

 

Inflammasome Assays In Vitro and in Mouse Models. 

Guo H, Ting JP.

Curr Protoc Immunol. 2020 Dec;131(1):e107. doi: 10.1002/cpim.107.

PMID: 33017103

 

CUE: CpG impUtation ensemble for DNA methylation levels across the human methylation450 (HM450) and EPIC (HM850) BeadChip platforms. 

Li G, Raffield L, Logue M, Miller MW, Santos HP Jr, O’Shea TM, Fry RC, Li Y.

Epigenetics. 2020 Oct 4:1-11. doi: 10.1080/15592294.2020.1827716. Online ahead of print.

PMID: 33016200

 

Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence. 

Walens A, Lin J, Damrauer JS, McKinney B, Lupo R, Newcomb R, Fox DB, Mabe NW, Gresham J, Sheng Z, Sibley AB, De Buysscher T, Kelkar H, Mieczkowski PA, Owzar K, Alvarez JV.

Nat Commun. 2020 Oct 6;11(1):5017. doi: 10.1038/s41467-020-18730-z.

PMID: 33024122

 

Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life. 

Jiménez JA, Ptacek TS, Tuttle AH, Schmid RS, Moy SS, Simon JM, Zylka MJ.

Mol Autism. 2020 Oct 5;11(1):74. doi: 10.1186/s13229-020-00369-8.

PMID: 33023670

 

Genome-Wide Association Analysis of Neonatal White Matter Microstructure. 

Zhang J, Xia K, Ahn M, Jha SC, Blanchett R, Crowley JJ, Szatkiewicz JP, Zou F, Zhu H, Styner M, Gilmore JH, Knickmeyer RC.

Cereb Cortex. 2020 Oct 3:bhaa266. doi: 10.1093/cercor/bhaa266. Online ahead of print.

PMID: 33009551

 

An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation. 

Lerner AM, Hepperla AJ, Keele GR, Meriesh HA, Yumerefendi H, Restrepo D, Zimmerman S, Bear JE, Kuhlman B, Davis IJ, Strahl BD.

Genome Res. 2020 Oct 5. doi: 10.1101/gr.264283.120. Online ahead of print.

PMID: 33020206