Department of Genetics faculty, postdocs, students and collaborators published fifteen papers during March 10-23, 2019.
| Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes. | |
| Fang Z, Weng C, Li H, Tao R, Mai W, Liu X, Lu L, Lai S, Duan Q, Alvarez C, Arvan P, Wynshaw-Boris A, Li Y, Pei Y, Jin F, Li Y. | |
| Cell Rep. 2019 Mar 12;26(11):3132-3144.e7. doi: 10.1016/j.celrep.2019.02.043. | |
| PMID: 30865899 |
| Mapping causal pathways from genetics to neuropsychiatric disorders using genome-wide imaging genetics: current status and future directions. | |
| Le BD, Stein JL. | |
| Psychiatry Clin Neurosci. 2019 Mar 13. doi: 10.1111/pcn.12839. [Epub ahead of print] | |
| PMID: 30864184 |
| vqtl: An R Package for Mean-Variance QTL Mapping. | |
| Corty RW, Valdar W. | |
| G3 (Bethesda). 2018 Dec 10;8(12):3757-3766. doi: 10.1534/g3.118.200642. | |
| PMID: 30389795 |
| QTL Mapping on a Background of Variance Heterogeneity. | |
| Corty RW, Valdar W. | |
| G3 (Bethesda). 2018 Dec 10;8(12):3767-3782. doi: 10.1534/g3.118.200790. | |
| PMID: 30389794 |
| Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice. | |
| Corty RW, Kumar V, Tarantino LM, Takahashi JS, Valdar W. | |
| G3 (Bethesda). 2018 Dec 10;8(12):3783-3790. doi: 10.1534/g3.118.200194. | |
| PMID: 30389793 |
| The three-dimensional landscape of the genome in human brain tissue unveils regulatory mechanisms leading to schizophrenia risk. | |
| Mah W, Won H. | |
| Schizophr Res. 2019 Mar 17. pii: S0920-9964(19)30089-1. doi: 10.1016/j.schres.2019.03.007. [Epub ahead of print] Review. | |
| PMID: 30894290 |
| Evidence that the human cell cycle is a series of uncoupled, memoryless phases. | |
| Chao HX, Fakhreddin RI, Shimerov HK, Kedziora KM, Kumar RJ, Perez J, Limas JC, Grant GD, Cook JG, Gupta GP, Purvis JE. | |
| Mol Syst Biol. 2019 Mar 18;15(3):e8604. doi: 10.15252/msb.20188604. | |
| PMID: 30886052 |
| Reciprocal F1 Hybrids of Two Inbred Mouse Strains Reveal Parent-of-Origin and Perinatal Diet Effects on Behavior and Expression. | |
| Oreper D, Schoenrock SA, McMullan R, Ervin R, Farrington J Miller DR, de Villena FP, Valdar W, Tarantino LM,. | |
| G3 (Bethesda). 2018 Nov 6;8(11):3447-3468. doi: 10.1534/g3.118.200135. | |
| PMID: 30171036 |
| High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq. | |
| Simon JM, Paranjape SR, Wolter JM, Salazar G, Zylka MJ. | |
| Sci Rep. 2019 Mar 14;9(1):4529. doi: 10.1038/s41598-019-39016-5. | |
| PMID: 30872602 |
| Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1. | |
| McCann JV, Xiao L, Kim DJ, Khan OF, Kowalski PS, Anderson DG, Pecot CV, Azam SH, Parker JS, Tsai YS, Wolberg AS, Turner SD, Tatsumi K, Mackman N, Dudley AC. | |
| J Clin Invest. 2019 Mar 11;130. pii: 123106. doi: 10.1172/JCI123106. eCollection 2019 Mar 11. | |
| PMID: 30855280 |
| RNA-Sequencing of Umbilical Cord Blood to Investigate Spontaneous Preterm Birth: A Pilot Study. | |
| Vora NL, Parker JS, Mieckowski PA, Smeester L, Fry RC, Boggess KA. | |
| AJP Rep. 2019 Jan;9(1):e60-e66. doi: 10.1055/s-0039-1678717. Epub 2019 Mar 7. | |
| PMID: 30854245 |
| A Case Study of Genomic Instability in an Industrial Strain of <i>Saccharomyces cerevisiae</i>. | |
| Rodrigues-Prause A, Sampaio NMV, Gurol TM, Aguirre GM, Sedam HNC, Chapman MJ, Malc EP, Ajith VP, Chakraborty P, Tizei PA, Pereira GAG, Mieczkowski PA, Nishant KT, Argueso JL. | |
| G3 (Bethesda). 2018 Nov 6;8(11):3703-3713. doi: 10.1534/g3.118.200446. | |
| PMID: 30254181 |
| Centrosome Loss Triggers a Transcriptional Program To Counter Apoptosis-Induced Oxidative Stress. | |
| Poulton JS, McKay DJ, Peifer M. | |
| Genetics. 2019 Mar 13. pii: genetics.302051.2019. doi: 10.1534/genetics.119.302051. [Epub ahead of print] | |
| PMID: 30867197 |
| Next-Generation Sequencing (NGS) Methods Show Superior or Equivalent Performance to Non-NGS Methods on BRAF, EGFR, and KRAS Proficiency Testing Samples. | |
| Surrey LF, Oakley FD, Merker JD, Long TA, Vasalos P, Moncur JT, Kim AS. | |
| Arch Pathol Lab Med. 2019 Mar 13. doi: 10.5858/arpa.2018-0394-CP. [Epub ahead of print] | |
| PMID: 30865489 |
| Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation. | |
| Leatham-Jensen M, Uyehara CM, Strahl BD, Matera AG, Duronio RJ, McKay DJ. | |
| PLoS Genet. 2019 Jan 30;15(1):e1007932. doi: 10.1371/journal.pgen.1007932. eCollection 2019 Jan. | |
| PMID: 30699116 |