Congratulations to Graydon (Grey) Gereau, graduate student from the McElligott lab, on his first-author paper exploring neurotensin transmission through the brain-body connection!
Abstract
“The neurotensin system spans across the central nervous system, to the enteric nervous system (gut), and the periphery to govern behaviors and physiological responses that tune energy balance to maintain homeostasis. Neurotensin transmission is not only modulated by metabolic signals, neurotensin transmission itself can also impact metabolic state by exerting control over consumption, physical activity, and satiety signals. Many responses to sensory experiences and sleep processes are dictated by neurotensinergic activity via mechanisms that allow the organism to balance energy seeking and utilization to thrive in its environment. Given the broad reach neurotensin signaling has across the homeostatic landscape, understanding this system as a whole and examining new ways to target this system for therapeutic efficacy across many different conditions is necessary.”
Full Citation: Gereau GB, Garrison SD, McElligott ZA. Neurotensin and energy balance. J Neurochem. 2023 Jun 13. doi: 10.1111/jnc.15868. Epub ahead of print. PMID: 37309600.
