Clinical Trials

Screening Population

 

 

Diagnostic Population

A Multicenter Study to Test the Non-Inferiority of Digital Breast Tomosynthesis (DBT) Compared to Full-Field Digital Mammography (FFDM) in Detecting Breast Cancer (Part 2: Recruitment Plan for Asymptomatic Women Referred for Diagnostic Mammography)


(UNC PI - Pisano)

Brief Synopsis: This study will compare 3D Digital Breast Tomosynthesis (DBT) mammography to conventional 2D Full-Field Digital Mammography for early detection of breast cancer for patients coming in for diagnostic mammography.

This study is currently closed to accrual. Currently in follow-up phase.

A Multicenter Study to Test the Non-Inferiority of Digital Breast Tomosynthesis (DBT) Compared to Full-Field Digital Mammography (FFDM) in Detecting Breast Cancer (Part 3: Recruitment Plan for Asymptomatic Women Referred for Biopsy)


(UNC PI - Pisano)

Brief Synopsis: This study will compare 3D Digital Breast Tomosynthesis (DBT) mammography to conventional 2D Full-Field Digital Mammography for early detection of breast cancer for patients coming in for breast biopsy.

This study is currently closed to accrual. Currently in follow-up phase.

Radiologists' Preference Study - Digital Breast Tomosynthesis

 

(UNC PI - Pisano)

Brief Synopsis:  This study will compare radiologists' preference for digital breast tomosynthesis versus digital mammography in regards to lesion characteristic visibility. 

This study is closed to accrual.  Currently in reader study phase.

Breast Cancer Population (Treatment Planning/Treatment Response Monitoring)

Prospective Multicenter Study of the Role of Positron Emission Mammography in Pre-Surgical Planning for Breast Cancer


(UNC PI - Pisano)
Brief Synopsis: This study will compare Positron Emission Mammography (PEM) and Magnetic Resonance Imaging (MRI) to determine their ability to accurately identify, locate and measure the size of breast tumors in breast cancer patients.

This study is currently closed to accural. Currently in analysis phase.

ACRIN 6657 – The Use of MRI for Treatment Response to Neoadjuvant Chemotherapy for women with Diagnosis of Breast Cancer


(UNC PI – Pisano)
Brief Synopsis – Assessment of the use of MRI in determining patient response to neoadjuvant chemotherapy.

The study is currently open to accural. If you are a UNC patient interested in participating in this study, please contact Laura Tuttle (919) 966-2881.